Evidence map›Paper›PMID 34769162›Full record

ArticleInternational journal of molecular sciences2021

Anti-Melanoma Capability of Contactless Cold Atmospheric Plasma Treatment.

Dayun Yan, Qihui Wang, Xiaoliang Yao, Alisa Malyavko, Michael Keidar

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Targeting proteostasis pathways for cancer therapy.Journal of pharmaceutical analysis · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Plasma Biology 2.0.International journal of molecular sciences · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dayun YanDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.ORCID 0000-0002-9801-021X
Qihui WangDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.
Xiaoliang YaoDepartment of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA.
Alisa MalyavkoSchool of Medicine and Health Science, George Washington University, Washington, DC 20052, USA.ORCID 0000-0002-1515-1843
Michael KeidarSchool of Medicine and Health Science, George Washington University, Washington, DC 20052, USA.ORCID 0000-0003-0869-4310
George Washington University · US

Funding

National Science Foundation 1747760
6 · The paper itself

Abstract

In this study, we demonstrated that the widely used cold atmospheric plasma (CAP) jet could significantly inhibit the growth of melanoma cells using a contactless treatment method, The flow rate of helium gas was a key operational parameter to modulate electromagnetic (EM) effect on melanoma cells. Metal sheets with different sizes could be used as a strategy to control the strength of EM effect. More attractive, the EM effect from CAP could penetrate glass/polystyrene barriers as thick as 7 mm. All these discoveries presented the profound non-invasive nature of a physically based CAP treatment, which provided a solid foundation for CAP-based cutaneous/subcutaneous tumor therapy.

Indexed as

AnimalsHeliumHumansMelanomaMelanoma, ExperimentalMicePlasma GasesSkin NeoplasmsHeliumPlasma Gasescold plasmacontactless treatmentmelanoma treatmentnon-invasive

Identifiers

PMID34769162
PMCPMC8584098
OpenAlexW3211014812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.