Evidence map›Paper›PMID 34769136›Full record

ArticleInternational journal of molecular sciences2021

Collecting Duct-Specific CR6-Interacting Factor-1-Deletion Aggravates Renal Inflammation and Fibrosis Induced by Unilateral Ureteral Obstruction.

Jin Young Jeong, Ki Ryang Na, Jin Ah Shin, Kwang-Sun Suh, Jwa-Jin Kim, Kang Wook Lee, Dae Eun Choi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jin Young JeongDepartment of Nephrology, Chungnam National University School of Medicine, Daejeon 35015, Korea.
Ki Ryang NaDepartment of Nephrology, Chungnam National University School of Medicine, Daejeon 35015, Korea.
Jin Ah ShinDepartment of Medical Science, Chungnam National University School of Medicine, Daejeon 35015, Korea.
Kwang-Sun SuhDepartment of Pathology, Chungnam National University School of Medicine, Daejeon 35015, Korea.ORCID 0000-0003-3874-864X
Jwa-Jin KimDepartment of Nephrology, Chungnam National University School of Medicine, Daejeon 35015, Korea.
Kang Wook LeeDepartment of Nephrology, Chungnam National University School of Medicine, Daejeon 35015, Korea.
Dae Eun ChoiDepartment of Nephrology, Chungnam National University School of Medicine, Daejeon 35015, Korea.ORCID 0000-0003-2870-3958
Chungnam National University · KR

Funding

National Research Foundation of Korea NRF-2021R1F1A1050858
6 · The paper itself

Abstract

Although inflammation and fibrosis, which are key mechanisms of chronic kidney disease, are associated with mitochondrial damage, little is known about the effects of mitochondrial damage on the collecting duct in renal inflammation and fibrosis. To generate collecting duct-specific mitochondrial injury mouse models, CR6-interacting factor-1 (CRIF1)

Indexed as

AnimalsCell Cycle ProteinsDisease Models, AnimalKidney Tubules, CollectingMaleMiceMice, Inbred C57BLMice, KnockoutMitochondriaOxidative StressRenal Insufficiency, ChronicUreteral ObstructionCell Cycle ProteinsCrif1 protein, mousecollecting ductCre-loxpCRIF1fibrosisinflammationkidneymitochondria

Identifiers

PMID34769136
PMCPMC8584192
OpenAlexW3210304689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.