Evidence map›Paper›PMID 34769126›Full record

ArticleInternational journal of molecular sciences2021

Monocytes and Macrophages Serve as Potent Prostaglandin D

Sonja Rittchen, Katharina Jandl, Ilse Lanz, Bernhard Reiter, Nerea Ferreirós, Daniel Kratz, Jörg Lindenmann, Luka Brcic, Thomas Bärnthaler, Reham Atallah and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Metabolic adaptation of glucose-deprived macrophages involves partial gluconeogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Coactosin-Like Protein Reduces Prostaglandin DAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Sonja RittchenOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-8753-4384
Katharina JandlOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.
Ilse LanzOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.
Bernhard ReiterOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.
Nerea FerreirósPharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe University Frankfurt, 60596 Frankfurt am Main, Germany.
Daniel KratzPharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe University Frankfurt, 60596 Frankfurt am Main, Germany.
Jörg LindenmannDepartment of Surgery, Divison of Thoracic and Hyperbaric Surgery, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0003-1276-7666
Luka BrcicDiagnostic and Research Institute of Pathology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-9098-8416
Thomas BärnthalerOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-4988-3700
Reham AtallahOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0001-7184-4882
Horst OlschewskiLudwig Boltzmann Institute for Lung Vascular Research, 8010 Graz, Austria.ORCID 0000-0002-2834-7466
Eva M SturmOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.
Akos HeinemannOtto Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-8554-2372
Medical University of Graz · ATGoethe University Frankfurt · DE

Funding

Austrian Science Fund FWF DOC 31
6 · The paper itself

Abstract

Acute respiratory inflammation, most commonly resulting from bacterial or viral infection, is one of the leading causes of death and disability worldwide. The inflammatory lipid mediator prostaglandin D

Indexed as

Acute Lung InjuryAnimalsHumansIntramolecular OxidoreductasesLipocalinsMacrophages, AlveolarMiceMonocytesProstaglandin D2Intramolecular OxidoreductasesLipocalinsProstaglandin D2prostaglandin R2 D-isomeraseacute lung injuryhPGDSlipopolysaccharidemononuclear phagocytesprecision-cut lung slicesprostaglandin D2

Identifiers

PMID34769126
PMCPMC8584273
OpenAlexW3209139407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.