Evidence map›Paper›PMID 34769111›Full record

ArticleInternational journal of molecular sciences2021

Involvement of GPR17 in Neuronal Fibre Outgrowth.

Max Braune, Nico Scherf, Claudia Heine, Katja Sygnecka, Thanigaimalai Pillaiyar, Chiara Parravicini, Bernd Heimrich, Maria P Abbracchio, Christa E Müller, Heike Franke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Purinergic Signaling in Neuroinflammation.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Max BrauneRudolf Boehm Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Härtelstr. 16-18, 04107 Leipzig, Germany.
Nico ScherfMethods and Development Group Neural Data Analysis and Statistical Computing, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstraße 1A, 04103 Leipzig, Germany.
Claudia HeineRudolf Boehm Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Härtelstr. 16-18, 04107 Leipzig, Germany.
Katja SygneckaRudolf Boehm Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Härtelstr. 16-18, 04107 Leipzig, Germany.
Thanigaimalai PillaiyarDepartment of Pharmaceutical & Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.ORCID 0000-0001-5575-8896
Chiara ParraviciniDepartment of Pharmaceutical Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.ORCID 0000-0002-4115-0094
Bernd HeimrichDepartment of Neuroanatomy, Institute of Anatomy and Cell Biology, Center for Basics in NeuroModulation, Faculty of Medicine, University of Freiburg, Albertstr. 23, 79104 Freiburg, Germany.
Maria P AbbracchioDepartment of Pharmaceutical Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy.
Christa E MüllerDepartment of Pharmaceutical & Medicinal Chemistry, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.ORCID 0000-0002-0013-6624
Heike FrankeRudolf Boehm Institute of Pharmacology and Toxicology, Medical Faculty, University of Leipzig, Härtelstr. 16-18, 04107 Leipzig, Germany.ORCID 0000-0001-7126-6146
Leipzig University · DEUniversity of Bonn · DEUniversity of Milan · ITMax Planck Institute for Human Cognitive and Brain Sciences · DEUniversity of Freiburg · DE

Funding

Federal Ministry of Education and Research PtJ-Bio 0315883, 0313909Fondazione Cariplo 2008.2907
6 · The paper itself

Abstract

Characterization of new pharmacological targets is a promising approach in research of neurorepair mechanisms. The G protein-coupled receptor 17 (GPR17) has recently been proposed as an interesting pharmacological target, e.g., in neuroregenerative processes. Using the well-established

Indexed as

AcetatesAnimalsAnimals, NewbornCoculture TechniquesCyclopropanesDrug Evaluation, PreclinicalFemaleLeukotriene AntagonistsMaleNerve RegenerationNeuronal OutgrowthQuinolinesRatsReceptors, G-Protein-CoupledSulfidesAcetatesCyclopropanesGPR17 protein, ratLeukotriene AntagonistsmontelukastQuinolinesReceptors, G-Protein-CoupledSulfidesex vivo organotypic brain slice co-cultureG protein-coupled receptor 17 (GPR17)montelukastneurite outgrowthneurodegeneration and neuroregenerationNG2

Identifiers

PMID34769111
PMCPMC8584086
OpenAlexW3208291573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.