Evidence map›Paper›PMID 34769092›Full record

ArticleInternational journal of molecular sciences2021

11,12 Epoxyeicosatrienoic Acid Rescues Deteriorated Wound Healing in Diabetes.

Katharina Sommer, Heike Jakob, Caroline Reiche, Dirk Henrich, Jasmina Sterz, Johannes Frank, Ingo Marzi, Anna Lena Sander

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Katharina SommerDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.
Heike JakobDepartment of Trauma, Hand and Reconstructive Surgery, Marienhausklinik St. Josef Kohlhof, 66539 Neunkirchen, Germany.
Caroline ReicheDepartment of Surgery, Hospital Bad Soden, 65812 Bad Soden, Germany.
Dirk HenrichDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.ORCID 0000-0002-9728-4032
Jasmina SterzDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.
Johannes FrankDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.
Ingo MarziDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.
Anna Lena SanderDepartment of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe-University, 60596 Frankfurt am Main, Germany.
Goethe University Frankfurt · DEMesser (Germany) · DESt. Josef Krankenhaus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epoxyeicosatrienoic acids (EET) facilitate regeneration in different tissues, and their benefit in dermal wound healing has been proven under normal conditions. In this study, we investigated the effect of 11,12 EET on dermal wound healing in diabetes. We induced diabetes by i.p. injection of streptozotocin 2 weeks prior to wound creation on the dorsal side of the mouse ear. 11,12 EET was applied every second day on the wound, whereas the control groups received only solvent. Epithelialization was monitored every second day

Indexed as

8,11,14-Eicosatrienoic AcidAnimalsDiabetes ComplicationsDiabetes Mellitus, ExperimentalDrug Evaluation, PreclinicalInflammationMaleMiceNeovascularization, PhysiologicWound Healing11,12-epoxy-5,8,14-eicosatrienoic acid8,11,14-Eicosatrienoic AciddiabetesEETinflammatory reactionneovascularizationproliferationwound repair

Identifiers

PMID34769092
PMCPMC8583902
OpenAlexW3208692848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.