Evidence map›Paper›PMID 34769029›Full record

ArticleInternational journal of molecular sciences2021

Involvement of the miR-363-5p/P2RX4 Axis in Regulating Schwann Cell Phenotype after Nerve Injury.

Eun-Jung Sohn, Yun-Kyeong Nam, Hwan-Tae Park

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Optogenetic and Endogenous Modulation of CaInternational journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eun-Jung SohnDepartment of Molecular Neuroscience, College of Medicine, Dong-A University, Busan 602-714, Korea.ORCID 0000-0001-6095-5106
Yun-Kyeong NamDepartment of Molecular Neuroscience, College of Medicine, Dong-A University, Busan 602-714, Korea.
Hwan-Tae ParkDepartment of Molecular Neuroscience, College of Medicine, Dong-A University, Busan 602-714, Korea.
Dong-A University · KRPusan National University · KR

Funding

National Research Foundation of Korea 2016R1A5A2007009National Research Foundation of Korea 2018R1D1A1B07043762National Research Foundation of Korea 2021R1I1A1A01052609
6 · The paper itself

Abstract

Although microRNAs (miRNAs or miRs) have been studied in the peripheral nervous system, their function in Schwann cells remains elusive. In this study, we performed a microRNA array analysis of cyclic adenosine monophosphate (cAMP)-induced differentiated primary Schwann cells.

Indexed as

AnimalsCells, CulturedDown-RegulationFemaleMiceMice, Inbred C57BLMicroRNAsMyelin SheathPeripheral Nerve InjuriesPhenotypePregnancyRatsRats, Sprague-DawleyReceptors, Purinergic P2X4Schwann CellsSignal TransductionmicroRNA 363, mouseMicroRNAsP2rx4 protein, mouseReceptors, Purinergic P2X4microRNAmiRNA 363-5pSchwann cellsWallerian degeneration

Identifiers

PMID34769029
PMCPMC8584002
OpenAlexW3208397795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.