Evidence map›Paper›PMID 34769028›Full record

ArticleInternational journal of molecular sciences2021

Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase.

Jia-Qi Lu, Wei-Wei Shi, Meng-Jie Xiao, Yun-Sang Tang, Yong-Tang Zheng, Pang-Chui Shaw

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jia-Qi LuCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Wei-Wei ShiBayRay Innovation Center, Shenzhen Bay Laboratory, Shenzhen 518107, China.
Meng-Jie XiaoCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Yun-Sang TangCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Yong-Tang ZhengKey Laboratory of Animal Models and Human Disease Mechanisms, National Kunming High Level Biosafety Research Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.ORCID 0000-0001-5469-0324
Pang-Chui ShawCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Chinese University of Hong Kong · HKKunming Institute of Zoology · CNShenzhen Bay Laboratory · CN

Funding

The Chinese University of Hong Kong 3110130The Research Grants Council of Hong Kong SAR 14176617
6 · The paper itself

Abstract

Ribosome-inactivating proteins (RIPs) hydrolyze the N-glycosidic bond and depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA. In this study, we have purified and characterized lyophyllin, an unconventional RIP from

Indexed as

AgaricalesAmino Acid SequenceAnimalsBase SequenceEndoribonucleasesFungal ProteinsHeLa CellsHep G2 CellsHumansPeptide HydrolasesProtein BindingRatsRibosome Inactivating ProteinsRicinRNA, Ribosomal, 28Salpha-sarcinEndoribonucleasesFungal ProteinsPeptide HydrolasesRibosome Inactivating ProteinsRicinRNA, Ribosomal, 28SlyophyllinN-glycosidasepeptidase M35 superfamilyribosome-inactivating proteins

Identifiers

PMID34769028
PMCPMC8584072
OpenAlexW3210597669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.