Evidence map›Paper›PMID 34768921›Full record

ArticleInternational journal of molecular sciences2021

PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway.

Shin Pai, Vijesh Kumar Yadav, Kuang-Tai Kuo, Narpati Wesa Pikatan, Chun-Shu Lin, Ming-Hsien Chien, Wei-Hwa Lee, Michael Hsiao, Shao-Chih Chiu, Chi-Tai Yeh and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 75 citations in OpenAlex.

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  14. Dichloroacetate for Cancer Treatment: Some Facts and Many Doubts.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  15. About a Possible Impact of Endodontic Infections byInternational journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Shin PaiGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Vijesh Kumar YadavDepartment of Medical Research and Education, Taipei Medical University-Shuang Ho Hospital, New Taipei City 235, Taiwan.ORCID 0000-0002-2679-1205
Kuang-Tai KuoDivision of Thoracic Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0003-2754-2283
Narpati Wesa PikatanDepartment of Medical Research and Education, Taipei Medical University-Shuang Ho Hospital, New Taipei City 235, Taiwan.
Chun-Shu LinDepartment of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0003-1919-8769
Ming-Hsien ChienGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-0084-7231
Wei-Hwa LeeDepartment of Medical Research and Education, Taipei Medical University-Shuang Ho Hospital, New Taipei City 235, Taiwan.ORCID 0000-0003-0932-3191
Michael HsiaoGenomics Research Center, Academia Sinica, Taipei 115, Taiwan.ORCID 0000-0001-8529-9213
Shao-Chih ChiuGraduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan.
Chi-Tai YehGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-5189-9755
Jo-Ting TsaiGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Taipei Medical University-Shuang Ho Hospital · TWYuanpei University · TWChina Medical University · TWGenomics Research Center, Academia Sinica · TWSt. Martin de Porres Hospital · TWTaipei Medical University · TWTri-Service General Hospital · TW

Funding

National Taiwan University of Science and Technology TMU-SHH-001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedApoptosisCD47 AntigenCell Line, TumorCisplatinDisease ProgressionDNA DamageEpithelial-Mesenchymal TransitionFemaleGlycolysisHumansMaleMiddle AgedMouth NeoplasmsProto-Oncogene Proteins c-aktBX795CD47 AntigenCD47 protein, humanCisplatinPDK1 protein, humanProto-Oncogene Proteins c-aktPyrimidinesPyruvate Dehydrogenase Acetyl-Transferring KinaseRNA, Small InterferingThiophenescancer stem cellsCD47chemo/radioresistanceglycolysisOSCCPDK1

Identifiers

PMID34768921
PMCPMC8584253
OpenAlexW3209628825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.