Evidence map›Paper›PMID 34768904›Full record

ArticleInternational journal of molecular sciences2021

Mutants of the Zebrafish K

Roberto Rodríguez-Ortiz, Ataúlfo Matínez-Torres

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Zebrafish as a Model for Neurological Disorders.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roberto Rodríguez-OrtizCátedras CONACyT-Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus UNAM-Juriquilla, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.
Ataúlfo Matínez-TorresDepartamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Campus UNAM-Juriquilla, Universidad Nacional Autónoma de México, Querétaro CP 76230, Mexico.
Universidad Nacional Autónoma de México · MX

Funding

Consejo Nacional de Ciencia y Tecnología A1-S-10450Consejo Nacional de Ciencia y Tecnología A1-S-7659PAPIIT-UNAM IN204520
6 · The paper itself

Abstract

Epilepsy is a chronic neurological disorder that affects 50 million people worldwide. The most common form of epilepsy is idiopathic, where most of the genetic defects of this type of epilepsy occur in ion channels. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarization, and are mainly expressed in the heart and central and peripheral nervous systems. In humans, four HCN genes have been described, and emergent clinical data shows that dysfunctional HCN channels are involved in epilepsy.

Indexed as

Behavior, AnimalMutationAnimalsEpilepsyHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsNeuronsSeizuresZebrafishZebrafish ProteinsHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsZebrafish Proteinsabsence seizuresepilepsyHCN channelszebrafish

Identifiers

PMID34768904
PMCPMC8584164
OpenAlexW3209546558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.