Evidence map›Paper›PMID 34768833›Full record

ArticleInternational journal of molecular sciences2021

Polyphenol Metabolite Pyrogallol-

Daniela F Santos, Mariana Pais, Cláudia N Santos, Gabriela A Silva

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniela F SantosiNOVA4HEALTH, CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
Mariana PaisiNOVA4HEALTH, CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
Cláudia N SantosiNOVA4HEALTH, CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0002-5809-1924
Gabriela A SilvaiNOVA4HEALTH, CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal.
Universidade Nova de Lisboa · PT

Funding

European Research Council European Union's Horizon 2020 Research and Innovation Programme under Grant Agreement No. 804229Fundação para a Ciência e Tecnologia PD/BD/114251/2016; EXPL-BIM-MEC-1433-2013; PTDC/BTM/ORG/28121/2017iNOVA4Health UID/Multi/04462/2013
6 · The paper itself

Abstract

(Poly)phenol-derived metabolites are small molecules resulting from (poly)phenol metabolization after ingestion that can be found in circulation. In the last decade, studies on the impact of (poly)phenol properties in health and cellular metabolism accumulated evidence that (poly)phenols are beneficial against human diseases. Diabetic retinopathy (DR) is characterized by inflammation and neovascularization and targeting these is of therapeutic interest. We aimed to study the effect of pyrogallol-

Indexed as

AnimalsCell LineDiabetes Mellitus, ExperimentalDiabetic RetinopathyEye ProteinsHumansInflammationMaleMiceMice, Inbred C57BLMicrogliaNeovascularization, PathologicNerve Growth FactorsPolyphenolsPyrogallolRetinaEye ProteinsNerve Growth FactorsPolyphenolsPyrogallolStreptozocinSulfatesVascular Endothelial Growth Factor Avascular endothelial growth factor A, mousediabetic retinopathyhyperglycemiainflammationneovascularizationretinal pigment epithelium

Identifiers

PMID34768833
PMCPMC8583739
OpenAlexW3210478908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.