Evidence map›Paper›PMID 34768815›Full record

ArticleInternational journal of molecular sciences2021

A Combined mRNA- and miRNA-Sequencing Approach Reveals miRNAs as Potential Regulators of the Small Intestinal Transcriptome in Celiac Disease.

Ineke Luise Tan, Donatella Barisani, Roberto Panceri, Rutger Modderman, Marijn Visschedijk, Rinse K Weersma, Cisca Wijmenga, Iris Jonkers, Rodrigo Coutinho de Almeida, Sebo Withoff

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Circulating MicroRNAs and Cytokines Associated with Celiac Disease.Middle East journal of digestive diseases · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Celiac disease: From genetics to epigenetics.World journal of gastroenterology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ineke Luise TanDepartment of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Donatella BarisaniSchool of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0003-4592-6221
Roberto PanceriFondazione MBBM, S. Gerardo Hospital, 20900 Monza, Italy.
Rutger ModdermanDepartment of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Marijn VisschedijkDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Rinse K WeersmaDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Cisca WijmengaDepartment of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-5635-1614
Iris JonkersDepartment of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Rodrigo Coutinho de AlmeidaSection Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Sebo WithoffDepartment of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-7704-3437
University Medical Center Groningen · NLAzienda Ospedaliera San Gerardo · ITLeiden University Medical Center · NLUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CeD) is triggered by gluten and results in inflammation and villous atrophy of the small intestine. We aimed to explore the role of miRNA-mediated deregulation of the transcriptome in CeD. Duodenal biopsies of CeD patients (

Indexed as

InflammationLipid MetabolismTranscriptomeAutoimmunityCeliac DiseaseDuodenumFemaleHumansInterferonsMaleMicroRNAsRNA, MessengerSequence Analysis, RNASignal TransductionInterferonsMicroRNAsRNA, MessengerautoimmunitymiRNA‒target gene regulationpost-translational transcript regulation

Identifiers

PMID34768815
PMCPMC8583991
OpenAlexW3205375629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.