Evidence map›Paper›PMID 34768802›Full record

ArticleInternational journal of molecular sciences2021

PRC1 Stabilizes Cardiac Contraction by Regulating Cardiac Sarcomere Assembly and Cardiac Conduction System Construction.

Xixia Peng, Gang Feng, Yanyong Zhang, Yuhua Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  8. Article
  9. The Polycomb group geneFrontiers in neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xixia PengInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0002-4940-8029
Gang FengInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0003-4054-6828
Yanyong ZhangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Yuhua SunInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0001-7902-9022
Chinese Academy of Sciences · CN

Funding

National Natural Science Foundation of China 31671526Strategic Priority Research Program of Chinese Academy of Sciences XDB31000000
6 · The paper itself

Abstract

Cardiac development is a complex process that is strictly controlled by various factors, including PcG protein complexes. Several studies have reported the critical role of PRC2 in cardiogenesis. However, little is known about the regulation mechanism of PRC1 in embryonic heart development. To gain more insight into the mechanistic role of PRC1 in cardiogenesis, we generated a PRC1 loss-of-function zebrafish line by using the CRISPR/Cas9 system targeting

Indexed as

Muscle ContractionAnimalsAnimals, Genetically ModifiedEmbryonic DevelopmentHeartLoss of Function MutationMyocardiumPolycomb Repressive Complex 1SarcomeresUbiquitin-Protein LigasesZebrafishZebrafish ProteinsPolycomb Repressive Complex 1rnf2 protein, zebrafishUbiquitin-Protein LigasesZebrafish Proteinscardiac conduction systemcardiac contractionPRC1Rnf2sarcomere assembly

Identifiers

PMID34768802
PMCPMC8583368
OpenAlexW3206869029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.