Evidence map›Paper›PMID 34768755›Full record

ArticleInternational journal of molecular sciences2021

The Influence of Tea Tree Oil on Antifungal Activity and Pharmaceutical Characteristics of Pluronic

Magdalena Wróblewska, Emilia Szymańska, Katarzyna Winnicka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Nano-Enabled Advances in Tea Tree Essential Oil (Materials (Basel, Switzerland) · 2026
    Review
  3. Relevance of topical application of minoxidil laden nano-lipid for hair growth enhancement.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Synthetic and Natural Antifungals-Desirable and Hazardous Effects.International journal of molecular sciences · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Magdalena WróblewskaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Białystok, A. Mickiewicza 2c, 15-222 Białystok, Poland.ORCID 0000-0002-5782-679X
Emilia SzymańskaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Białystok, A. Mickiewicza 2c, 15-222 Białystok, Poland.ORCID 0000-0003-0355-8598
Katarzyna WinnickaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Białystok, A. Mickiewicza 2c, 15-222 Białystok, Poland.ORCID 0000-0002-1013-610X
Medical University of Białystok · PL

Funding

Medical University of Białystok SUB/2/NN/21/001/2215
6 · The paper itself

Abstract

Fungal skin infections are currently a major clinical problem due to their increased occurrence and drug resistance. The treatment of fungal skin infections is based on monotherapy or polytherapy using the synergy of the therapeutic substances. Tea tree oil (TTO) may be a valuable addition to the traditional antifungal drugs due to its antifungal and anti-inflammatory activity. Ketoconazole (KTZ) is an imidazole antifungal agent commonly used as a treatment for dermatological fungal infections. The use of hydrogels and organogel-based formulations has been increasing for the past few years, due to the easy method of preparation and long-term stability of the product. Therefore, the purpose of this study was to design and characterize different types of Pluronic

Indexed as

AdhesivenessAnimalsAntifungal AgentsCandida parapsilosisChemistry, PharmaceuticalDrug LiberationGelsKetoconazoleKineticsLecithinsMiceMicroscopy, Electron, ScanningModels, BiologicalModels, TheoreticalPoloxamerRheologyAntifungal AgentsGelsKetoconazoleLecithinsPoloxamerTea Tree Oilantifungal activitygelsin vitro releaseketoconazolepermeationPluronic® F-127tea tree oil

Identifiers

PMID34768755
PMCPMC8582737
OpenAlexW3210866210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.