Evidence map›Paper›PMID 34768596›Full record

ArticleJournal of clinical medicine2021

Karyotype Abnormalities in the X Chromosome Predict Response to the Growth Hormone Therapy in Turner Syndrome.

Jakub Kasprzyk, Marcin Włodarczyk, Aleksandra Sobolewska-Włodarczyk, Katarzyna Wieczorek-Szukała, Renata Stawerska, Maciej Hilczer, Andrzej Lewiński

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. [Reflections on the clinical diagnosis and management of Turner syndrome].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jakub KasprzykDrewnica Masovian Voivodship Hospital, 05-091 Ząbki, Poland.
Marcin WłodarczykDepartment of General and Oncological Surgery, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0001-9118-4623
Aleksandra Sobolewska-WłodarczykDepartment of Gastroenterology, Medial University of Lodz, 92-213 Lodz, Poland.
Katarzyna Wieczorek-SzukałaDepartment of Endocrinology and Metabolic Diseases, Medical University of Lodz, 93-338 Lodz, Poland.
Renata StawerskaDepartment of Pediatric Endocrinology, Medical University of Lodz, 93-338 Lodz, Poland.ORCID 0000-0002-0508-2186
Maciej HilczerDepartment of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital-Research Institute, 93-338 Lodz, Poland.
Andrzej LewińskiDepartment of Endocrinology and Metabolic Diseases, Medical University of Lodz, 93-338 Lodz, Poland.ORCID 0000-0002-8748-3337
Medical University of Lodz · PLPolish Mother’s Memorial Hospital Research Institute · PLUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short stature is characteristic for Turner syndrome (TS) patients, and particular karyotype abnormalities of the X chromosome may be associated with different responsiveness to recombinant human GH (rhGH) therapy. The aim of the study was to analyze the effect of different types of TS karyotype abnormalities on the response to rhGH therapy. A total of 57 prepubertal patients with TS treated with rhGH with a 3 year follow-up were enrolled in the study and categorized according to their karyotype as X monosomy (

Indexed as

growth hormone therapykaryotype abnormalitiesturner syndrome

Identifiers

PMID34768596
PMCPMC8584940
OpenAlexW3209087223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.