Evidence map›Paper›PMID 34768589›Full record

ArticleJournal of clinical medicine2021

Evaluation of Vascular Endothelial Function in Children with Type 1 Diabetes Mellitus.

Karolina Nocuń-Wasilewska, Danuta Zwolińska, Agnieszka Zubkiewicz-Kucharska, Dorota Polak-Jonkisz

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Beyond HbAFrontiers in endocrinology · 2026
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karolina Nocuń-WasilewskaDepartment of Pediatric Nephrology, Wroclaw Medical Univeristy, 50-367 Wrocław, Poland.
Danuta ZwolińskaDepartment of Pediatric Nephrology, Wroclaw Medical Univeristy, 50-367 Wrocław, Poland.
Agnieszka Zubkiewicz-KucharskaDepartment of Pediatric Endocrinology and Diabetology, Wroclaw Medical University, 50-367 Wrocław, Poland.ORCID 0000-0002-6641-6776
Dorota Polak-JonkiszDepartment of Pediatric Nephrology, Wroclaw Medical Univeristy, 50-367 Wrocław, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic kidney disease belongs to the major complications of diabetes mellitus. Here, hyperglycaemia is a key metabolic factor that causes endothelial dysfunction and vascular changes within the renal glomerulus. The aim of the present study was to assess the function of the vascular endothelium in children with type 1 diabetes mellitus (type 1 diabetes) by measuring selected endothelial lesion markers in blood serum. The selected markers of endothelial lesions (sVCAM-1, sICAM-1, sE-SELECTIN, PAI-1, ADMA and RAGE) were assayed by the immunoenzymatic ELISA method. The study involved 66 patients (age: 5-18 years) with type 1 diabetes and 21 healthy controls (age: 5-16 years). In the type 1 diabetes patients, significantly higher concentrations of all of the assayed markers were observed compared to the healthy controls (

Indexed as

childrendiabetic kidney diseaseeGFRvascular endothelial markers

Identifiers

PMID34768589
PMCPMC8584312
OpenAlexW3208495793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.