Evidence map›Paper›PMID 34768577›Full record

ArticleJournal of clinical medicine2021

One-Year Outcome of Glycoprotein IIb/IIIa Inhibitor Therapy in Patients with Myocardial Infarction-Related Cardiogenic Shock.

Krzysztof Myrda, Mariusz Gąsior, Dariusz Dudek, Bartłomiej Nawrotek, Jacek Niedziela, Wojciech Wojakowski, Marek Gierlotka, Marek Grygier, Janina Stępińska, Adam Witkowski and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Krzysztof MyrdaSilesian Center for Heart Diseases, 3rd Department of Cardiology, 41-800 Zabrze, Poland.ORCID 0000-0002-5564-6920
Mariusz GąsiorSilesian Center for Heart Diseases, 3rd Department of Cardiology, 41-800 Zabrze, Poland.
Dariusz DudekInstitute of Cardiology, Jagiellonian University Medical College, 31-088 Kraków, Poland.
Bartłomiej NawrotekClinical Department of Interventional Cardiology, John Paul II Hospital, 31-202 Kraków, Poland.
Jacek NiedzielaSilesian Center for Heart Diseases, 3rd Department of Cardiology, 41-800 Zabrze, Poland.
Wojciech WojakowskiDepartment of Cardiology and Structural Heart Diseases, 3rd Division of Cardiology, Medical University of Silesia, 40-055 Katowice, Poland.
Marek GierlotkaDepartment of Cardiology, Institute of Medicine, University of Opole, 45-040 Opole, Poland.ORCID 0000-0001-5639-2128
Marek Grygier1st Department of Cardiology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.
Janina StępińskaInstitute of Cardiology, 04-628 Warszawa, Poland.
Adam WitkowskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warszawa, Poland.
Maciej Lesiak1st Department of Cardiology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.ORCID 0000-0003-2630-5016
Jacek LegutkoInstitute of Cardiology, Jagiellonian University Medical College, 31-088 Kraków, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate the effect of intravenous glycoprotein IIb/IIIa receptor inhibitors (GPIs) on in-hospital survival and mortality during and at the 1-year follow-up in patients undergoing percutaneous coronary intervention (PCI) for myocardial infarction (MI) complicated by cardiogenic shock (CS), who were included in the Polish Registry of Acute Coronary Syndromes (PL-ACS).

methodsFrom 2003 to 2019, 466,566 MI patients were included in the PL-ACS registry. A total of 10,193 patients with CS received PCI on admission. Among them, GPIs were used in 3934 patients.

resultsThe patients treated with GPIs were younger, had lower systolic blood pressure on admission, required inotropes and intra-aortic balloon pump (IABP) support more frequently, and showed a lower efficacy of coronary angioplasty. In both groups, the same rates of in-hospital adverse events were observed. A lower mortality rate was reported in the group treated with GPIs 12 months after admission (54.9% vs. 57.9%,

conclusionsThe addition of GPIs to the standard pharmacotherapy combined with PCI in patients with MI and CS on admission reduced the risk of death in the 12-month follow-up period without increasing in-hospital adverse event rates.

Indexed as

acute coronary syndromecardiogenic shockglycoprotein IIb/IIIa receptor inhibitorsmyocardial infarctionpercutaneous coronary intervention

Identifiers

PMID34768577
PMCPMC8584341

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.