Evidence map›Paper›PMID 34768567›Full record

ArticleJournal of clinical medicine2021

Impact of Rhythm vs. Rate Control in Atrial Fibrillation on the Long-Term Outcome of Patients Undergoing Transcatheter Edge-to-Edge Mitral Valve Repair.

Christian Waechter, Felix Ausbuettel, Georgios Chatzis, Juan Cheko, Dieter Fischer, Holger Nef, Sebastian Barth, Philipp Halbfass, Thomas Deneke, Sebastian Kerber and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Christian WaechterDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0003-1558-0696
Felix AusbuettelDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0003-0526-7989
Georgios ChatzisDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0002-7685-4470
Juan ChekoDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.
Dieter FischerDepartment of Cardiology, Cardiovascular Center Rotenburg/Fulda, Heinz-Meise-Straße 100, 36199 Rotenburg/Fulda, Germany.ORCID 0000-0003-4458-2631
Holger NefDepartment of Cardiology, Cardiovascular Center Rotenburg/Fulda, Heinz-Meise-Straße 100, 36199 Rotenburg/Fulda, Germany.ORCID 0000-0002-2823-3928
Sebastian BarthDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Von-Guttenberg-Straße 11, 97616 Bad Neustadt/Saale, Germany.ORCID 0000-0001-9549-3503
Philipp HalbfassDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Von-Guttenberg-Straße 11, 97616 Bad Neustadt/Saale, Germany.ORCID 0000-0002-4291-2417
Thomas DenekeDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Von-Guttenberg-Straße 11, 97616 Bad Neustadt/Saale, Germany.ORCID 0000-0003-1379-1684
Sebastian KerberDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Von-Guttenberg-Straße 11, 97616 Bad Neustadt/Saale, Germany.ORCID 0000-0001-5256-3823
Jan KikecDepartment of Cardiology, Cardiovascular Center Bad Neustadt/Saale, Von-Guttenberg-Straße 11, 97616 Bad Neustadt/Saale, Germany.ORCID 0000-0002-7233-3010
Hans-Helge MuellerInstitute for Bioinformatics and Biostatistics, Philipps University, Bunsenstraße 3, 35037 Marburg, Germany.ORCID 0000-0001-7364-5377
Dimitar DivchevDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0002-3062-3271
Bernhard SchiefferDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0001-6677-7486
Ulrich LuesebrinkDepartment of Cardiology, University Hospital Marburg, Baldingerstraße, 35043 Marburg, Germany.ORCID 0000-0002-7588-1602
Philipps University of Marburg · DERhön-Klinikum · DECardiovascular Center Frankfurt · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is a highly prevalent comorbidity in patients with severe mitral valve regurgitation (MR) undergoing transcatheter mitral valve repair (TMVR) and has been shown to significantly worsen their outcome. However, data on the impact of AF treatment strategy in this rapidly growing cohort of patients is unknown. In a multicenter, observational cohort study, 542 consecutive patients undergoing TMVR were enrolled, and subsequently, comprehensive survival analyses according to AF status and therapy were performed using propensity score matching and Cox regression. In the analyzed cohort, 373 (73.3%) of the TMVR patients had concomitant AF. Of these patients, 212 (59%) were on rate control therapy and 161 (41%) were on rhythm control therapy. At 3 years, significantly reduced cumulative survival was observed for patients on rhythm compared to patients on rate control (46.7% (75/161) vs. 56.5% (91/161),

Indexed as

elderlyheart failureMitraClipmitral regurgitationpharmacological rhythm controlrate-controlrhythm-control

Identifiers

PMID34768567
PMCPMC8584691
OpenAlexW3210148757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.