Evidence map›Paper›PMID 34768520›Full record

ArticleJournal of clinical medicine2021

Myofascial Induction Therapy Improves the Sequelae of Medical Treatment in Head and Neck Cancer Survivors: A Single-Blind, Placebo-Controlled, Randomized Cross-Over Study.

Eduardo Castro-Martín, Noelia Galiano-Castillo, Carolina Fernández-Lao, Lucía Ortiz-Comino, Paula Postigo-Martin, Manuel Arroyo-Morales

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06148077 (Effects of Manual Therapy on Oral Opening, Swallow Function, and Upper Quarter Mobility in Chilean Survivors of Head and Neck Cancer), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06148077 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Manual Therapy on Oral Opening, Swallow Function, and Upper Quarter Mobility in Chilean Survivors of Head and Neck Cancer: A Study Protocol for a Controlled, Randomized Study (MATEO Study, MAnual ThErapy for Oral Opening).

TypeinterventionalSponsorUniversidad de La FronteraRan2024 to 2025Enrolled70ConditionsHead and Neck Cancer, Trismus, DysfunctionArmsManual Therapy, Motor control exercises
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. The effects of myofascial induction therapy in survivors of head and neck cancer: a randomized, controlled clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  2. Review
  3. Chronic Pain in the Cancer Survivor.Current pain and headache reports · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eduardo Castro-MartínDepartment of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Noelia Galiano-CastilloDepartment of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-6825-4213
Carolina Fernández-LaoDepartment of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-9392-1532
Lucía Ortiz-Comino'Cuídate' Support Unit for Oncology Patients, 18016 Granada, Spain.ORCID 0000-0003-2710-8890
Paula Postigo-MartinDepartment of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.ORCID 0000-0001-6430-5207
Manuel Arroyo-MoralesDepartment of Physical Therapy, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Universidad de Granada · ES

Funding

University of Granada. Proyectos de Investigación Precompetitivos para Jóvenes Investigadores. Plan Propio 2020 PPJIA2020.15
6 · The paper itself

Abstract

Head and neck cancer (HNC) is the sixth most common cancer worldwide. Yet, less than 60% of HNC survivors receive adequate therapy for treatment-related sequelae. The objective of this study was to determine the efficacy of myofascial induction therapy (MIT) in improving cervical and shoulder pain and range of motion, maximal mouth opening, and cervical muscle function in HNC survivors. This crossover, blinded, placebo-controlled study involved 22 HNC survivors (average age 56.55 ± 12.71) of which 13 were males (59.1%) who received, in a crossover fashion, both a single 30-min session of MIT in the form of manual unwinding and simulated pulsed shortwave therapy (placebo), with a 4-week washout interval between the two. Cervical and shoulder pain (visual analogue scale) and range of motion (cervical range of motion device and goniometer), maximum mouth opening (digital caliper), and cervical muscle function (deep cervical flexor endurance test) were measured before and after the treatment and placebo sessions. A single session of MIT improved cervical and affected side shoulder pain, cervical range of motion, maximum mouth opening, and cervical muscle function. The associated effect sizes ranged from moderate to large. The present study suggests that MIT, in the form of manual unwinding, improves cervical (-3.91 ± 2.77) and affected-side shoulder (-3.64 ± 3.1) pain, cervical range of motion (flexion: 8.41 ± 8.26 deg; extension: 12.23 ± 6.55; affected-side rotation: 14.27 ± 11.05; unaffected-side rotation: 11.73 ± 8.65; affected-side lateroflexion: 7.95 ± 5.1; unaffected-side lateroflexion: 9.55 ± 6.6), maximum mouth opening (3.36 ± 3.4 mm), and cervical muscle function (8.09 ± 6.96 s) in HNC survivors.

Indexed as

head and neck neoplasmsmusculoskeletal manipulationspainrange of motion

Identifiers

PMID34768520
PMCPMC8584513
OpenAlexW3209221971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.