Evidence map›Paper›PMID 34768508›Full record

ArticleJournal of clinical medicine2021

Isolated Growth Hormone Deficiency and Idiopathic Short Stature: Comparative Efficiency after Growth Hormone Treatment up to Adult Height.

Ana-Belen Ariza-Jimenez, Isabel Leiva Gea, Maria Jose Martinez-Aedo Ollero, Juan Pedro Lopez-Siguero

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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  4. Effects ofJournal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ana-Belen Ariza-JimenezPediatric Endocrinology, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.ORCID 0000-0002-0585-0886
Isabel Leiva GeaPediatric Endocrinology, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.ORCID 0000-0002-2259-7253
Maria Jose Martinez-Aedo OlleroPediatric Endocrinology, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Juan Pedro Lopez-SigueroPediatric Endocrinology, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.ORCID 0000-0001-9282-9139
Hospital Regional Universitario de Málaga · ESFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTreatment with growth hormone (GH) is not approved for idiopathic short stature (ISS) in Europe.

objectivesTo compare the growth of children treated with isolated GH deficiency (IGHD) vs. ISS-treated and untreated children.

methodsA retrospective descriptive study of patients treated in the last 14 years for IGHD (Group A), in comparison with ISS-treated (Group B) and untreated (Group C) subjects.

resultsGroup A had 67 males, who showed a height gain of 1.24 SD. Group B had 30 boys, who showed a height gain of 1.47 SD. Group C had 42 boys, who showed an improvement of 0.37 SD. The final heights were -1.52 SD, -1.31 SD, and -2.03 SD, respectively. Group A and C did not reach their target heights (with differences of 0.27 SD and 0.59 SD, respectively). Group B surpassed their target height by 0.29 SD.

conclusionsThe final heights of the IGHD and treated ISS are similar. Treated groups were taller than untreated groups.

Indexed as

final heightgrowth hormone deficiencygrowth hormone treatmentidiopathic short stature

Identifiers

PMID34768508
PMCPMC8585059
OpenAlexW3208192604

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.