Evidence map›Paper›PMID 34768402›Full record

ReviewJournal of clinical medicine2021

The Burden of Peritoneal Metastases from Gastric Cancer: A Systematic Review on the Incidence, Risk Factors and Survival.

Anouk Rijken, Robin J Lurvink, Misha D P Luyer, Grard A P Nieuwenhuijzen, Felice N van Erning, Johanna W van Sandick, Ignace H J T de Hingh

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05347524 (Detection of Peritoneal Metastasis of Gastric Cancer by Liquid Biopsy in Peripheral Blood), which is not on this map. Cited by 71 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05347524 recruitingnot on this mapstarted 2022, after this paper: background citation

Detection of Peritoneal Metastasis of Gastric Cancer by Liquid Biopsy in Peripheral Blood: A Prospective Study

TypeobservationalSponsorShanghai Zhongshan HospitalRan2022 to 2030Enrolled384ConditionsCancerArmsBaseline blood draw and blood-based biomarkers analyses
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anouk RijkenDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands.
Robin J LurvinkDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands.
Misha D P LuyerDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands.ORCID 0000-0002-9483-1520
Grard A P NieuwenhuijzenDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands.
Felice N van ErningDepartment of Research and Development, Netherlands Comprehensive Cancer Organization, 3511 DT Utrecht, The Netherlands.
Johanna W van SandickDepartment of Surgery, Antoni van Leeuwenhoek-Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Ignace H J T de HinghDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The peritoneum is a common metastatic site in gastric cancer. This systematic review provides an overview of the incidence, risk factors and survival of synchronous peritoneal metastases from gastric cancer. A systematic search was performed to identify studies wherein the incidence, risk factors and survival of gastric cancer with peritoneal metastases were investigated. Of all 38 potentially eligible studies, 17 studies were included based on the eligibility criteria. The incidence of synchronous gastric peritoneal metastases was reviewed for population-based studies (10-21%), for observational cohort studies (2-15%) and for surgical cohort studies (13-40%). Potential risk factors for synchronous gastric peritoneal metastases were younger age, non-cardia gastric cancer, female sex, signet ring cell carcinoma, diffuse type histology or linitis plastica, T4 stage, Hispanic ethnicity and more than one metastatic location. Synchronous peritoneal metastases are commonly diagnosed in patients with gastric cancer with an incidence up to 21% in recent population-based studies. Furthermore, prognosis of patients with gastric peritoneal metastases is poor with median overall survival ranging from 2 to 9 months. The high incidence and poor prognosis require intensive research on diagnostic features and effective treatment options to improve survival.

Indexed as

gastric cancerincidenceperitoneal metastasessurvivaltreatment

Identifiers

PMID34768402
PMCPMC8584453

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.