ReviewJournal of clinical medicine2021
Conservative Management of Uterine Adenomyosis: Medical vs. Surgical Approach.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 56 citations in OpenAlex.
- Treatment selection for adenomyosis based on imaging findings and patient characteristics.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Review
- Role of oral gonadotropin-releasing hormone antagonists in the management of uterine adenomyosis: a narrative review.Reproduction & fertility · 2026Review
- The interaction between inflammation and estrogen in adenomyosis : from molecular mechanisms to therapeutic strategies.Seminars in immunopathology · 2026Review
- A Narrative Review and Risk-Stratification Framework for Preventing LNG-IUS Expulsion in Adenomyosis.Therapeutics and clinical risk management · 2026Review
- Impact of Minimally Invasive Surgery on Quality of Life and Infertility in Deep Infiltrating Endometriosis.Journal of clinical medicine · 2025Review
- Retrospective cohort study on the efficacy and safety of high-intensity focused ultrasound in non-invasive treatment of uterine leiomyomas and adenomyosis.Abdominal radiology (New York) · 2025Article
- Comparative analysis of the clinical efficacy of conservative treatment for adenomyosis using traditional Chinese medicine and Western medicine.Journal of health, population, and nutrition · 2025Article
- The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis.Scientific reports · 2025Article
- Progressively diminished estrogen signaling concordant with increased fibrosis in ectopic endometrium.Human reproduction open · 2025Article
- Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring.Frontiers in medicine · 2025Article
- Case Report: Heterotopic pregnancy after adenomyosis surgery: a rare case highlighting diagnostic pitfalls and clinical insights.Frontiers in medicine · 2025Article
- Recurrence rates and associated risk factors after conservative surgery for adenomyosis: a retrospective study.BMC women's health · 2024Article
- Research Advances in Adenomyosis-Related Signaling Pathways and Promising Targets.Biomolecules · 2024Review
- Adenomyosis and Adolescence: A Challenging Diagnosis and Complex Management.Diagnostics (Basel, Switzerland) · 2024Review
- Prolactin and Hyperprolactinaemia in Endometriosis-Related Infertility: Are There Clinically Significant Connections?Journal of clinical medicine · 2024Review
- Expression of Endometrial Receptivity Markers throughout the Menstrual Cycle in Women with and without Uterine Adenomyosis.Journal of clinical medicine · 2024Article
- An age-period-cohort analysis of hysterectomy incidence trends in Germany from 2005 to 2019.Scientific reports · 2024Article
- Laparoscopic adenomyomectomy combined with levonorgestrel-releasing intrauterine system is effective for long-term management of adenomyosis.BMC women's health · 2024Article
- Uterine rupture due to adenomyosis in an adolescent: A case report and review of literature.World journal of clinical cases · 2023Article
- The Present and the Future of Medical Therapies for Adenomyosis: A Narrative Review.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Uterine adenomyosis is a commonly encountered estrogen-dependent disease in reproductive-age women, causing heavy menstrual bleeding, intense pelvic pain, and infertility. Although adenomyosis was previously considered a disease of multiparous women, it is becoming increasingly evident that it also affects younger nulliparous women and may compromise their fertility potential. It is clear that hysterectomy, the standard approach to definitively manage the disease, is not an option for patients wishing to preserve their fertility, so there is an urgent need to develop novel conservative strategies. We searched the current literature for available methods for conservative management of adenomyosis, including both pharmacological and surgical approaches. There is no existing drug that can cure adenomyosis at present, but some off-label treatment options may be used to tackle disease symptoms and improve fertility outcomes. Adenomyosis in patients wishing to conceive can be 'treated' by conservative surgery, though these procedures require highly experienced surgeons and pose a considerable risk of uterine rupture during subsequent pregnancies. While currently available options for conservative management of adenomyosis do have some capacity for alleviating symptoms and enhancing patient fertility perspectives, more effective new options are needed, with gonadotropin-releasing hormone antagonists showing encouraging results in preliminary studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.