ArticleJournal of clinical medicine2021
Reproductive, Obstetric and Neonatal Outcomes in Women with Congenital Uterine Anomalies: A Systematic Review and Meta-Analysis.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Non-genetic risk factors of miscarriage: a comprehensive umbrella review of systematic review and meta-analysis.Reproductive health · 2025Pooled it
- Assisted reproductive technology outcomes in women with congenital uterine anomalies: a systematic review.Archives of gynecology and obstetrics · 2024Pooled it
- Missed, Misclassified or Misunderstood? Clinician Perspectives on Congenital Uterine Anomalies in Australia and New Zealand.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Congenital Uterine Malformations and Pregnancy Outcomes: A Retrospective Observational Study to Inform Reproductive Counseling.Geburtshilfe und Frauenheilkunde · 2026Article
- Congenital Uterine Anomalies and Pregnancy Outcomes: A Population-Based Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Pregnancy Complications in Uterine Anomalies-A Pilot Study.Journal of clinical medicine · 2026Article
- Adverse Pregnancy Outcomes in Patients with Congenital Uterine Anomalies: Evaluation of a Population Dataset.American journal of perinatology · 2026Article
- Progesterone in recurrent pregnancy loss: from controversial efficacy to mechanism-based patient stratification.Frontiers in pharmacology · 2026Review
- A study of the association between the early pregnancy thrombosis-thyroid axis and pregnancy outcomes in patients with recurrent spontaneous abortion.Frontiers in endocrinology · 2026Article
- Association of concomitant laparoscopy with reproductive outcomes after hysteroscopic septum resection: a longitudinal cohort study.Frontiers in reproductive health · 2026Article
- Congenital complex uterine anomalies carry complex complications: an evaluation of ART outcomes.Journal of assisted reproduction and genetics · 2025Article
- Neonates at Risk: Understanding the Impact of High-Risk Pregnancies on Neonatal Health.Medicina (Kaunas, Lithuania) · 2025Review
- Obstetrical outcome in pregnant women presenting with congenital uterine anomalies.Pakistan journal of medical sciences · 2025Article
- Birth Outcomes in Pregnancies with Uterine Malformations: A Single-Center Retrospective Study.Journal of clinical medicine · 2025Article
- A survey on the frequency of polycystic ovary morphology (PCOM) in infertile patients with septate and arcuate uterine anomalies: a cross-sectional study.Scientific reports · 2025Article
- Diagnosis, Prevention, and Management of Fetal Growth Restriction (FGR).Journal of personalized medicine · 2024Review
- Impact of congenital uterine anomalies on obstetric and perinatal outcomes: systematic review and meta-analysis.Facts, views & vision in ObGyn · 2024Article
- A global scoping review of the circumstances of care seeking for abortion later in pregnancy.PLOS global public health · 2024Article
- Metroplasty increases the take-home baby rate by reducing pregnancy loss without changing the chance of conception in women with septate uterus: a retrospective, single-center, observational study.BMC pregnancy and childbirth · 2023Observational
- Analysis of hemi-uterus pregnancy outcomes in uterine malformations: a retrospective observational study.BMC pregnancy and childbirth · 2023Observational
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Congenital uterine anomalies (CUA) may influence reproductive performance, resulting in adverse pregnancy associated complications. This study aimed to assess the association of CUA subtypes with reproductive, obstetric, and perinatal outcomes. We performed a systematic search of the MEDLINE, EMBASE, and Cochrane libraries for studies comparing pregnancy outcomes between women with CUA and those with a normal uterus. The random effects model was used to estimate the odds ratios (ORs) with a 95% confidence interval (CI). Women with CUA had a lower rate of live births (OR 0.47; 95% CI 0.33-0.69), and a higher rate of first trimester miscarriage (OR, 1.79; 95% CI 1.34-2.4), second trimester miscarriage (OR 2.92; 95% CI 1.35-6.32), preterm birth (OR 2.98; 95% CI 2.43-3.65), malpresentation (OR 9.1; 95% CI 5.88-14.08), cesarean section (OR 2.87; 95% CI 1.56-5.26), and placental abruption (OR 3.12; 95% CI 1.58-6.18). Women with canalization defects appear to have the poorest reproductive performance during early pregnancy. However, unification defects were associated with obstetric and neonatal outcomes throughout the course of pregnancy. It may be beneficial for clinicians to advise on potential complications that may be increased depending on the type and severity of CUA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.