Evidence map›Paper›PMID 34768322›Full record

ArticleJournal of clinical medicine2021

The Role of Prostate Combination Biopsy Consisting of Targeted and Additional Systematic Biopsy.

Chung Un Lee, Joongwon Choi, Si Hyun Sung, Jae Hoon Chung, Wan Song, Minyong Kang, Hyun Hwan Sung, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon and 2 more

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Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chung Un LeeSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.ORCID 0000-0002-3030-0405
Joongwon ChoiDepartment of Urology, VHS Medical Center, Seoul 05368, Korea.ORCID 0000-0001-5978-8179
Si Hyun SungSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Jae Hoon ChungSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.ORCID 0000-0002-9729-3457
Wan SongSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Minyong KangSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Hyun Hwan SungSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Byong Chang JeongSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Seong Il SeoSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Seong Soo JeonSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Hyun Moo LeeSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.
Hwang Gyun JeonSamsung Medical Center, Department of Urology, School of Medicine Sungkyunkwan University, Seoul 06351, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo identify the role of combination biopsy, which consists of both targeted and additional systematic cores, in the diagnosis of clinically significant prostate cancer (csPCa).

methodsWe retrospectively reviewed patients with PSA levels 2.5-15 ng/mL who have a suspicious prostate lesion (with the Prostate Imaging Reporting and Data System (PI-RADS) ≥ 3) on multiparametric MRI (mpMRI) between January 2016 and December 2018. We analyzed biopsy results by PI-RADS score and biopsy methods (systematic, targeted, and combination biopsy).

resultsOf the 711 total patients, an average of 4.0 ± 1.8 targeted and 8.6 ± 3.1 additional systematic biopsies were performed. The additional systematic biopsies were sampled outside the targeted biopsy area. The combination biopsies detected more csPCa (201 patients, 28.3%) than did the targeted (175 patients, 24.6%) or systematic (124 patients, 17.4%) biopsies alone (

conclusionsCombination biopsy has the benefit of detecting csPCa in both initial and repeat biopsy when there is a suspicious lesion on mpMRI.

Indexed as

combinationprostate biopsyProstate Imaging Reporting and Data System (PI-RADS)systematic biopsytargeted biopsy

Identifiers

PMID34768322
PMCPMC8584506

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