Evidence map›Paper›PMID 34768287›Full record

ArticleZeitschrift fur Gastroenterologie2022

Red urine and a red herring - diagnosing rare diseases in the light of the COVID-19 pandemic.

Philipp Jud, Gerald Hackl, Alexander Christian Reisinger, Angela Horvath, Philipp Eller, Vanessa Stadlbauer

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Zeitschrift fur Gastroenterologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Philipp JudDepartment of Angiology, Medical University of Graz, Graz, Austria.
Gerald HacklIntensive Care Unit, Medical University of Graz, Graz, Austria.
Alexander Christian ReisingerIntensive Care Unit, Medical University of Graz, Graz, Austria.
Angela HorvathDepartment of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
Philipp EllerIntensive Care Unit, Medical University of Graz, Graz, Austria.
Vanessa StadlbauerDepartment of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.ORCID 0000-0001-5508-8271
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has occupied the time and resources of health care professionals for more than 1 year. The risk of missed diagnoses has been discussed in the medical literature, mainly for common diseases such as cancer and cardiovascular events. However, rare diseases also need appropriate attention in times of a pandemic. CASE REPORT: We report a 34-year-old woman with fever, pinprick sensation in her chest and thoracic spine, and dizziness after receiving the first dose of ChAdOx1 nCoV-19 vaccination. The patient's condition worsened with abdominal pain, red urine, and hyponatremia, needing intensive care admission. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) was diagnosed. Vaccine-induced thrombocytopenia and thrombosis were ruled out. Acute hepatic porphyria was finally diagnosed, and the patient recovered completely after treatment with hemin.

conclusionCurrently, the focus of physicians is on COVID-19 and associated medical problems, such as vaccine side effects. However, it is important to be vigilant for other uncommon medical emergencies in medically exceptional situations that may shift our perception.

Indexed as

COVID-19Inappropriate ADH SyndromeAdultChAdOx1 nCoV-19COVID-19 TestingFemaleHumansPandemicsRare DiseasesChAdOx1 nCoV-19

Identifiers

PMID34768287
PMCPMC9470277
OpenAlexW3213961087

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.