Evidence map›Paper›PMID 34768033›Full record

ArticlePediatric neurology2022

Acute Large Vessel Ischemic Stroke in Patients With COVID-19-Related Multisystem Inflammatory Syndrome.

Jaimie Chang, Zachary Bulwa, Hannah Breit, Laurel J Cherian, James J Conners, Sarah Y Song, Rima M Dafer

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Pediatric neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Advances in Management of the Stroke Etiology One-Percenters.Current neurology and neuroscience reports · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jaimie ChangDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
Zachary BulwaDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
Hannah BreitDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
Laurel J CherianDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
James J ConnersDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
Sarah Y SongDepartment of Neurology, Rush University Medical Center, Chicago, Illinois.
Rima M DaferDepartment of Neurology, Rush University Medical Center, Chicago, Illinois. Electronic address: Rima_Dafer@rush.edu.
Rush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute ischemic stroke (AIS) is rare in children, and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported. PATIENT DESCRIPTIONS: We two patients with AIS presenting with large vessel occlusive disease in previously healthy adolescents recently exposed to SARS-CoV-2 infection.

resultsBoth patients were subsequently diagnosed with and treated for MIS-C. Here, we discuss the course of their treatments and clinical responses.

conclusionEarly recognition and diagnosis of AIS with large vessel occlusion in children with MIS-C is critical to make available all treatment options to improve clinical outcomes.

Indexed as

AdolescentCOVID-19FemaleHumansIschemic StrokeSystemic Inflammatory Response SyndromeAcute ischemic infarctionCOVID-19Large vesselMIS-CSARS-Cov2Stroke

Identifiers

PMID34768033
PMCPMC8464033
OpenAlexW3204441697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.