Evidence map›Paper›PMID 34767710›Full record

ArticleJournal of the American Chemical Society2021

Enzymatic C

Zheng Cui, Han Nguyen, Minakshi Bhardwaj, Xiachang Wang, Martin Büschleb, Anke Lemke, Christian Schütz, Christian Rohrbacher, Pierre Junghanns, Stefan Koppermann and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Promiscuous Enzymes for Residue-Specific Peptide and Protein Late-Stage Functionalization.Chembiochem : a European journal of chemical biology · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Zheng CuiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
Han NguyenDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
Minakshi BhardwajDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.
Xiachang WangDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0002-1106-1904
Martin BüschlebDepartment of Chemistry, Institute of Organic and Biomolecular Chemistry, Georg-August-University, GöTammannstr. 2, 37077 Göttingen, Germany.
Anke LemkeDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.
Christian SchützDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.
Christian RohrbacherDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.
Pierre JunghannsDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.
Stefan KoppermannDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.
Christian DuchoDepartment of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.ORCID 0000-0002-0629-9993
Jon S ThorsonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0002-7148-0721
Steven G Van LanenDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0003-1539-2732
Saarland University · DEUniversity of Kentucky · USUniversity of Göttingen · DE

Funding

Biosynthesis of nucleoside antibiotics targeting bacterial translocase IR01AI087849 · NIAID · UNIVERSITY OF KENTUCKY · PI VAN LANEN, STEVEN GARY · 2011 to 2020
$3.3M
Biosynthesis and medicinal chemistry of the capuramycin antimycobacterial antibioticsR01AI128862 · NIAID · UNIVERSITY OF KENTUCKY · PI THORSON, JON SCOTT, VAN LANEN, STEVEN GARY · 2017 to 2021
$1.0M
NIAID NIH HHS R01 AI087849NIAID NIH HHS R01 AI128862
6 · The paper itself

Abstract

Muraymycins are peptidyl nucleoside antibiotics that contain two C

Indexed as

ArginineBiological ProductsLeucineMolecular StructurePeptidesPeptide SynthasesArginineBiological ProductsLeucinenon-ribosomal peptide synthasePeptidesPeptide Synthases

Identifiers

PMID34767710
PMCPMC10258837
OpenAlexW3214260205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.