Evidence map›Paper›PMID 34767667›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

Intramolecular N-H⋅⋅⋅F Hydrogen Bonding Interaction in a Series of 4-Anilino-5-Fluoroquinazolines: Experimental and Theoretical Characterization of Electronic and Conformational Effects.

Lorenz M Urner, Ga Young Lee, Joseph W Treacy, Aneta Turlik, Saeed I Khan, K N Houk, Michael E Jung

Open access · greenAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lorenz M UrnerDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
Ga Young LeeDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
Joseph W TreacyDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.ORCID http://orcid.org/0000-0002-8597-0246
Aneta TurlikDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.ORCID http://orcid.org/0000-0002-0907-8969
Saeed I KhanDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
K N HoukDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.ORCID http://orcid.org/0000-0002-8387-5261
Michael E JungDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
University of California, Los Angeles · US

Funding

Computational Investigations of Asymmetric Carbon-Carbon Bond FormationF32GM134709 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TURLIK, ANETA · 2021 to 2022
$90k
Frontier ScientificNIGMS NIH HHS F32 GM134709NIH HHS GM134709
6 · The paper itself

Abstract

The 4-anilino-6,7-ethylenedioxy-5-fluoroquinazoline scaffold is presented as a novel model system for the characterization of the weak NH⋅⋅⋅F hydrogen bonding (HB) interaction. In this scaffold, the aniline NH proton is forced into close proximity with the nearby fluorine (d

Indexed as

FluoridesFluorineElectronicsHydrogen BondingMolecular ConformationFluoridesFluorinefluorinehydrogen bondsNMR spectroscopynoncovalent interactionsquinazolines

Identifiers

PMID34767667
PMCPMC9482468
OpenAlexW3214352533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.