Evidence map›Paper›PMID 34767549›Full record

ArticlePLoS neglected tropical diseases2021

Seroprevalence of anti-SARS-CoV-2 IgG at the first epidemic peak in French Guiana, July 2020.

Claude Flamand, Christelle Alves Sarmento, Antoine Enfissi, Sarah Bailly, Emmanuel Beillard, Mélanie Gaillet, Céline Michaud, Véronique Servas, Nathalie Clement, Anaïs Perilhou and 11 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Dynamics of SARS-CoV-2 lineages in French Guiana in 2020-2021: 4 epidemic waves with cross-influences from Europe and South America.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
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  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Claude FlamandEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.ORCID 0000-0002-8064-445X
Christelle Alves SarmentoEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Antoine EnfissiLaboratory of Virology, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Sarah BaillyEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Emmanuel BeillardMedical Biology Laboratory, Institut Pasteur in French Guiana, Cayenne, French Guiana.ORCID 0000-0002-2546-7614
Mélanie GailletHealth Centers Department, Cayenne Hospital Center, Cayenne, French Guiana.
Céline MichaudHealth Centers Department, Cayenne Hospital Center, Cayenne, French Guiana.ORCID 0000-0001-5410-6298
Véronique ServasHealth Centers Department, Cayenne Hospital Center, Cayenne, French Guiana.
Nathalie ClementClinical Core of the Center for Translational Sciences, Institut Pasteur, Paris, France.
Anaïs PerilhouClinical Core of the Center for Translational Sciences, Institut Pasteur, Paris, France.
Thierry CarageCarage Medical Biology Laboratory, Kourou, French Guiana.
Didier MussoLaboratoires Eurofins Labazur Guyane, Remire, French Guiana.
Jean-François CarodMedical Biology laboratory, Centre Hospitalier de l'Ouest Guyanais, Saint-Laurent du Maroni, French Guiana.
Stéphanie EustacheEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Céline TourbillonEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Elodie BoizonEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Samantha JamesEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Félix DjossouInfectious and Tropical Diseases Unit, Cayenne Hospital Center, Cayenne, French Guiana.
Henrik SaljeMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, UMR2000, CNRS, Paris, France.
Simon CauchemezMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, UMR2000, CNRS, Paris, France.ORCID 0000-0001-9186-4549
Dominique RoussetLaboratory of Virology, Institut Pasteur in French Guiana, Cayenne, French Guiana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile Latin America has been heavily affected by the pandemic, only a few seroprevalence studies have been conducted there during the first epidemic wave in the first half of 2020. METHODOLOGY/PRINCIPAL

findingsA cross-sectional survey was performed between 15 July 2020 and 23 July 2020 among individuals who visited 4 medical laboratories or 5 health centers for routine screening or clinical management, with the exception of symptomatic suggestive cases of covid-19. Samples were screened for the presence of anti-SARS-CoV-2 IgG directed against domain S1 of the SARS-CoV-2 spike protein using the anti-SARS-CoV-2 enzyme-linked immunosorbent assay (ELISA) from Euroimmun. CONCLUSIONS/SIGNIFICANCE: The overall seroprevalence was 15.4% [9.3%-24.4%] among 480 participants, ranging from 4.0% to 25.5% across the different municipalities. The seroprevalence did not differ according to gender (p = 0.19) or age (p = 0.51). Among SARS-CoV-2 positive individuals, we found that 24.6% [11.5%-45.2%] reported symptoms consistent with COVID-19. Our findings revealed high levels of infection across the territory but a low number of resulting deaths, which can be explained by French Guiana's young population structure.

Indexed as

AdolescentAdultAgedAged, 80 and overAntibodies, ViralChildChild, PreschoolCOVID-19Cross-Sectional StudiesFrench GuianaHumansImmunoglobulin GInfantMiddle AgedSARS-CoV-2Seroepidemiologic StudiesAntibodies, ViralImmunoglobulin G

Identifiers

PMID34767549
PMCPMC8639096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.