Evidence map›Paper›PMID 34767481›Full record

Trial reportJCO oncology practice2022

Impact of Behavioral Nudges on the Quality of Serious Illness Conversations Among Patients With Cancer: Secondary Analysis of a Randomized Controlled Trial.

Eric H Li, William Ferrell, Tamar Klaiman, Pallavi Kumar, Nina O'Connor, Lynn M Schuchter, Jinbo Chen, Mitesh S Patel, Christopher R Manz, Ravi B Parikh

Registry-linked trialAbstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03984773 (A Stepped-Wedge Cluster Randomized Trial Using Machine-Generated Mortality Estimates and Behavioral Nudges to Promote Advance Care Planning Discussion Among Cancer Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03984773 nacompletednot on this map

A Stepped-Wedge Cluster Randomized Trial Using Machine-Generated Mortality Estimates and Behavioral Nudges to Promote Advance Care Planning Discussion Among Cancer Patients

TypeinterventionalSponsorUniversity of PennsylvaniaRan2019 to 2020Enrolled78ConditionsOncologyArmsNudge
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eric H LiPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-1385-1122
William FerrellPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-9966-1973
Tamar KlaimanPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Pallavi KumarPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-9896-4315
Nina O'ConnorPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Lynn M SchuchterPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Jinbo ChenPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-3174-2552
Mitesh S PatelPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Christopher R ManzDana Farber Cancer Institute, Boston, MA.ORCID 0000-0003-0928-3492
Ravi B ParikhPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-2692-6306

Funding

Human-Machine Collaborations to Improve Prognosis and Clinical Decision-Making in Advanced CancerK08CA263541 · NCI · UNIVERSITY OF PENNSYLVANIA · PI PARIKH, RAVI BHARAT · 2021 to 2025
$1.2M
NCI NIH HHS K08 CA263541
6 · The paper itself

Abstract

purposeSerious Illness Conversations (SICs) are structured conversations between clinicians and patients about prognosis, treatment goals, and end-of-life preferences. Although behavioral interventions may prompt earlier or more frequent SICs, their impact on the quality of SICs is unclear.

methodsThis was a secondary analysis of a randomized clinical trial (NCT03984773) among 78 clinicians and 14,607 patients with cancer testing the impact of an automated mortality prediction with behavioral nudges to clinicians to prompt more SICs. We analyzed 318 randomly selected SICs matched 1:1 by clinicians (159 control and 159 intervention) to compare the quality of intervention vs. control conversations using a validated codebook. Comprehensiveness of SIC documentation was used as a measure of quality, with higher integer numbers of documented conversation domains corresponding to higher quality conversations. A conversation was classified as high-quality if its score was ≥ 8 of a maximum of 10. Using a noninferiority design, mixed effects regression models with clinician-level random effects were used to assess SIC quality in intervention vs. control groups, concluding noninferiority if the adjusted odds ratio (aOR) was not significantly < 0.9.

resultsBaseline characteristics of the control and intervention groups were similar. Intervention SICs were noninferior to control conversations (aOR 0.99; 95% CI, 0.91 to 1.09). The intervention increased the likelihood of addressing patient-clinician relationship (aOR = 1.99; 95% CI, 1.23 to 3.27;

conclusionA behavioral intervention that increased SIC frequency did not decrease their quality. Behavioral prompts may increase SIC frequency without sacrificing quality.

Indexed as

CommunicationNeoplasmsDocumentationHumansPrognosis

Identifiers

PMID34767481
PMCPMC9014420

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.