Evidence map›Paper›PMID 34767466›Full record

SynthesisDento maxillo facial radiology2022

Is jaw fractal dimension a reliable biomarker for osteoporosis screening? A systematic review and meta-analysis of diagnostic test accuracy studies.

Davi de Sá Cavalcante, Paulo Goberlânio de Barros Silva, Francisco Samuel Rodrigues Carvalho, Ana Rosa Pinto Quidute, Lúcio Mitsuo Kurita, Adília Mirela Pereira Lima Cid, Thyciana Rodrigues Ribeiro, Marcela Lima Gurgel, Bianca Moreira Kurita, Fábio Wildson Gurgel Costa

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Dento maxillo facial radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Davi de Sá CavalcanteDivision of Radiology, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Paulo Goberlânio de Barros SilvaDivision of Oral Pathology, Christus Center University (UNICHRISTUS), Fortaleza, Ceará, Brazil.
Francisco Samuel Rodrigues CarvalhoDivision of Oral and Maxillofacial Surgery, Federal University of Ceará - campus Sobral, Sobral, Ceará, Brazil.ORCID 0000-0002-3142-1268
Ana Rosa Pinto QuiduteDivision of Endocrinology and Diabetology, Walter Cantídio University Hospital, Fortaleza, Ceará, Brazil.
Lúcio Mitsuo KuritaDivision of Radiology, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Adília Mirela Pereira Lima CidDivision of Radiology, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Thyciana Rodrigues RibeiroDivision of Patient with Special Needs, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Marcela Lima GurgelDivision of Radiology, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Bianca Moreira KuritaDivision of Pharmacology, Maurício de Nassau Center University, Fortaleza, Ceará, Brazil.
Fábio Wildson Gurgel CostaDivision of Radiology, Postgraduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo summarize the evidence on the feasibility of maxillomandibular imaging exams-related fractal dimension (FD) in screening patients with osteoporosis.

methodsThis registered systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy statement. High sensitivity search strategies were developed for six primary databases and grey literature. Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) items evaluated the risk of bias, and the GRADE approach assessed the evidence certainty.

resultsFrom 1034 records initially identified through database searching, four studies were included (total sample of 747 patients [osteoporosis, 136; control group, 611]). The meta-analysis showed that the overall sensitivity and specificity of the FD were 86.17 and 72.68%, respectively. In general, all studies showed low RoB and applicability concern. The certainty of the evidence was very low to moderate.

conclusionsThis systematic review showed that the jaw-related FD presented sensitivity and specificity values higher than 70%, and its sensitivity in osteoporosis screening was a better parameter than specificity.

Indexed as

FractalsOsteoporosisBiomarkersDiagnostic Tests, RoutineHumansSensitivity and SpecificityBiomarkersFractalsMandibleOsteoporosisPanoramic radiograph

Identifiers

PMID34767466
PMCPMC9499197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.