Evidence map›Paper›PMID 34767463›Full record

ArticleJCO global oncology2021

Dramatic Impact of Centralization and a Multidisciplinary Bladder Cancer Program in Reducing Mortality: The CABEM Project.

Fernando Korkes, Frederico Timóteo, Suelen Martins, Matheus Nascimento, Camila Monteiro, José H Santiago, Willy Baccaglini, Marcel A Silveira, Eduardo F Pedroso, Marcello M Gava and 3 more

Abstract read
In one paragraph

Article in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fernando KorkesDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.ORCID 0000-0003-4261-4345
Frederico TimóteoDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.ORCID 0000-0002-0731-3734
Suelen MartinsDivision of Oncology, Faculdade de Medicina do ABC, Santo André, Brazil.
Matheus NascimentoDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Camila MonteiroDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.ORCID 0000-0002-9042-1508
José H SantiagoDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Willy BaccagliniDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Marcel A SilveiraDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Eduardo F PedrosoDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Marcello M GavaDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.
Prashant PatelUniversity of Birmingham, Birmingham, United Kingdom.ORCID 0000-0002-2882-5990
Phillipe E SpiessMoffit Cancer Center, Tampa, FL.
Sidney GlinaDivision of Urology, Faculdade de Medicina do ABC, Santo André, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMuscle-invasive bladder cancer (MIBC) is an aggressive disease with a complex treatment. In Brazil, as in most developing countries, data are scarce, but mortality seems exceedingly high. We have created a centralization program involving a multidisciplinary clinic in a region comprising seven municipalities. The aim of this study is to evaluate the impact of a multidisciplinary clinic and a centralization-of-care program (CABEM program) on MIBC treatment in Brazil. PATIENTS AND

methodsA total of 116 consecutive patients were evaluated. In group 1, 58 patients treated for MIBC before establishing a bladder cancer program from 2011 to 2017 were retrospectively evaluated. Group 2 represented 58 patients treated for MIBC after the implementation of the CABEM centralization program. Age, sex, staging, comorbidity indexes, mortality rates, type of treatment, and perioperative outcomes were compared.

resultsPatients from group 2 versus 1 were older (68

conclusionOur data support that a centralization program, a structured bladder clinic associated with protocols, a multidisciplinary team, and inclusion of chemotherapy and radiotherapy treatments can pleasingly improve outcomes for patients with MIBC.

Indexed as

Urinary Bladder NeoplasmsCystectomyFemaleHumansMaleNeoadjuvant TherapyRetrospective StudiesUrinary Bladder

Identifiers

PMID34767463
PMCPMC8594663

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.