Evidence map›Paper›PMID 34767366›Full record

ArticleThe Journal of organic chemistry2021

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones.

Mohit Tyagi, Dan E Adolfsson, Pardeep Singh, Jörgen Ådén, Sanduni Wasana Jayaweera, Anna Gharibyan, Jaideep B Bharate, Anita Kiss, Souvik Sarkar, Anders Olofsson and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mohit TyagiDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Dan E AdolfssonDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Pardeep SinghDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Jörgen ÅdénDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Sanduni Wasana JayaweeraDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187 Umeå, Sweden.
Anna GharibyanDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187 Umeå, Sweden.
Jaideep B BharateDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0003-3269-6228
Anita KissDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Souvik SarkarDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.
Anders OlofssonDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187 Umeå, Sweden.
Fredrik AlmqvistDepartment of Chemistry, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0003-4646-0216
Umeå University · SE

Funding

Chemical disarming of drug resistance in Mycobacterium tuberculosisR01AI134847 · NIAID · WASHINGTON UNIVERSITY · PI ALMQVIST, FREDRIK, STALLINGS, CHRISTINA LEIGH · 2018 to 2021
$2.7M
NIAID NIH HHS R01 AI134847
6 · The paper itself

Abstract

Reaction of thiazoline fused 2-pyridones with alkyl halides in the presence of cesium carbonate opens the thiazoline ring via

Indexed as

CyclobutanesAlkenesAmyloid beta-PeptidesCycloaddition ReactionPyridonesAlkenesAmyloid beta-PeptidesCyclobutanesPyridones

Identifiers

PMID34767366
PMCPMC8650012
OpenAlexW3212807151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.