Evidence map›Paper›PMID 34767189›Full record

ReviewJournal of molecular neuroscience : MN2022

Emerging Role of Non-coding RNAs in Autism Spectrum Disorder.

Soudeh Ghafouri-Fard, Rezvan Noroozi, Serge Brand, Bashdar Mahmud Hussen, Reyhane Eghtedarian, Mohammad Taheri, Kaveh Ebrahimzadeh

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular neuroscience : MN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Circadian rhythm lncRNABiochemistry and biophysics reports · 2026
    Article
  3. Article
  4. Placental Alterations in Autism Spectrum Disorder: An In Silico Approach to circRNA-miRNA-mRNA Networks.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Assessment of Expression of lncRNAs in Autistic Patients.Journal of molecular neuroscience : MN · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Soudeh Ghafouri-FardDepartment of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rezvan NorooziMalopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.
Serge BrandPsychiatric Clinics, Center for Affective, Stress and Sleep Disorders, University of Basel, Basel, Switzerland.
Bashdar Mahmud HussenDepartment of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan Region, Iraq.
Reyhane EghtedarianMen's Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad TaheriUrology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mohammad_823@yahoo.com.ORCID http://orcid.org/0000-0001-8381-0591
Kaveh EbrahimzadehSkull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. dr.kavehmay1980@gmail.com.
Shahid Beheshti University of Medical Sciences · IRHawler Medical University · IQJagiellonian University · PLJena University Hospital · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorders (ASD) embrace a diverse set of neurodevelopmental diseases with a multifaceted genetic basis. Non-coding RNAs (ncRNAs) are among putative loci with critical participation in the development of ASD. Expression of some lncRNAs, namely RP11-466P24.2, SYP-AS1, STXBP5-AS1, and IFNG-AS1 has been decreased in ASD, while AK128569, CTD-2516F10.2, MSNP1AS, RPS10P2-AS1, LINC00693, LINC00689, NEAT1, TUG1, and Shank2-AS lncRNAs have been over-expressed in ASD. Expression of several miRNAs which are implicated in the immunological developmental, immune responses, and protein synthesis as well as those participating in the regulation of PI3K/Akt/mTOR and EGFR signaling pathways is dysregulated in the context of ASD. In the present article, we describe investigations which appraised the role of lncRNAs, miRNAs, and circRNAs in the pathobiology of ASD.

Indexed as

Autism Spectrum DisorderRNA, Long NoncodingHumansPhosphatidylinositol 3-KinasesPhosphatidylinositol 3-KinasesRNA, Long NoncodingAutism spectrum disordercircRNAlncRNAmiRNA

Identifiers

PMID34767189
OpenAlexW3214508375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.