Evidence map›Paper›PMID 34767179›Full record

ReviewJournal of gastrointestinal cancer2022

Potential Non-invasive Biomarkers of Helicobacter pylori-Associated Gastric Cancer.

Fatima Boubrik, Ahmed Belmouden, Nadia El Kadmiri

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Fecal miR-146a as a Non-Invasive Biomarker forLife (Basel, Switzerland) · 2026
    Article
  2. Article
  3. World journal of gastrointestinal oncology · 2025
    Review
  4. The Effect ofPathogens (Basel, Switzerland) · 2025
    Article
  5. Review
  6. The oncobiome; what, so what, now what?Microbiome research reports · 2025
    Review
  7. Article
  8. Chronic Atrophic Gastritis and Intestinal Metaplasia: A Latin American Perspective.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatima BoubrikLaboratory of Cell Biology and Molecular Genetics, Faculty of Science, Ibn Zohr University, Agadir, Morocco.
Ahmed BelmoudenLaboratory of Cell Biology and Molecular Genetics, Faculty of Science, Ibn Zohr University, Agadir, Morocco.
Nadia El KadmiriMolecular Engineering, Valorization and Environment Team, Polydisciplinary Faculty of Taroudant, Ibn Zohr University, Hay El Mohammadi (Lastah), Taroudannt, BP: 271, 83000, Morocco. n.elkadmiri@uiz.ac.ma.ORCID http://orcid.org/0000-0002-7032-9704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) remains the fifth most common incident cancer with the highest incidence in East Asian countries and the third leading cause of cancer death worldwide. The causal association between non-cardia GC and Helicobacter pylori (H. pylori) has been firmly documented by clinical and epidemiological studies. According to the guidelines for diagnosis and treatment of H. pylori infection, eradication therapy is strongly recommended. Early detection of GC is critical and can save lives through rapid technological advancement. At present, endoscopy remains the most efficient technique. However, it is invasive and costs highly.

methodsAn extensive bibliographic search was performed via PubMed/Medline, Web of Science, and EBSCO host databases to select studies conducted within the past 8 years. Forty-six relevant analyses were encompassed in this review.

resultsSeveral non-invasive candidate biomarkers associated with H. pylori, divided into virulence markers, transcriptome markers, genomic markers, and inflammatory markers, have been shown to be potential predictors of GC at an early stage.

conclusionThe discovery of non-invasive biomarkers offers new perspectives for screening, early detection, and monitoring of individuals at risk.

Indexed as

Helicobacter InfectionsHelicobacter pyloriStomach NeoplasmsBiomarkersEndoscopy, GastrointestinalHumansBiomarkersEarly detectionGastric cancer; H. pyloriNon-invasive biomarkers

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.