ReviewCellular and molecular neurobiology2023
Effect of Heat Stress on Hippocampal Neurogenesis: Insights into the Cellular and Molecular Basis of Neuroinflammation-Induced Deficits.
Review in Cellular and molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Warm season hourly temperature and psychiatric emergencies: A case-crossover study of a vulnerable population in Boston, 2005-2019.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Heat Stress Induces Cognitive Impairment Through ACSL4-Mediated Lipid Peroxidation and Subsequent Ferroptosis.Molecular neurobiology · 2026Article
- Heatwave-related variations in psychiatric consultations and admissions: a time-series analysis.Frontiers in psychiatry · 2026Article
- Research progress on the mechanisms and intervention strategies of microbiota-gut-brain axis dysfunction under heat stress.Frontiers in physiology · 2026Review
- Heat Stress-Mediated Multi-Organ Injury: Pathophysiology and Treatment Strategies.Comprehensive Physiology · 2025Review
- Heatwave and dementia: a systematic analysis for the Global Burden of Disease Study 2019.BMJ public health · 2025Article
- Heat stroke dysfunctions: from pathophysiology to prediction.Frontiers in physiology · 2025Review
- Genetic patterning in hippocampus of rat undergoing impaired spatial memory induced by long-term heat stress.Heliyon · 2024Article
- Heat stress induces calcium dyshomeostasis to subsequent cognitive impairment through ERS-mediated apoptosis via SERCA/PERK/eIF2α pathway.Cell death discovery · 2024Article
- How can heatstroke damage the brain? A mini review.Frontiers in neuroscience · 2024Review
- Editorial: Body temperature homeostasis: the biological thermostat.Frontiers in neuroscience · 2024Article
- Insulin-like growth factor 1 in heat stress-induced neuroinflammation: novel perspective about the neuroprotective role of chromium.Stress biology · 2023Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Heat stress is known to result in neuroinflammation, neuronal damage, and disabilities in learning and memory in animals and humans. It has previously been reported that cognitive impairment caused by neuroinflammation may at least in part be mediated by defective hippocampal neurogenesis, and defective neurogenesis has been linked to aberrantly activated microglial cells. Moreover, the release of cytokines within the brain has been shown to contribute to the disruption of cognitive functions in several conditions following neuroinflammation. In this review, we summarize evolving evidence for the current understanding of inflammation-induced deficits in hippocampal neurogenesis, and the resulting behavioral impairments after heat stress. Furthermore, we provide valuable insights into the molecular and cellular mechanisms underlying neuroinflammation-induced deficits in hippocampal neurogenesis, particularly relating to cognitive dysfunction following heat stress. Lastly, we aim to identify potential mechanisms through which neuroinflammation induces cognitive dysfunction, and elucidate how neuroinflammation contributes to defective hippocampal neurogenesis. This review may therefore help to better understand the relationship between hippocampal neurogenesis and heat stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.