Evidence map›Paper›PMID 34767133›Full record

ArticleCardiovascular drugs and therapy2023

cFLIP

Yun Zhao Li, Hui Wu, Di Liu, Jun Yang, Jian Yang, Jia Wang Ding, Gang Zhou, Jing Zhang, Dong Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular drugs and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yun Zhao LiInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Hui WuInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China. wuhui@ctgu.edu.cn.ORCID 0000-0001-5948-5987
Di LiuInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Jun YangInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Jian YangInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Jia Wang DingInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Gang ZhouInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Jing ZhangDepartment of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China.
Dong ZhangInstitute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
China Three Gorges University · CNYichang Central People's Hospital · CN

Funding

Master Thesis Training Fund of China Three Gorges University 2021SSPY105national natural science foundation of china 81600234natural science foundation of yichang city, china A20-2-001
6 · The paper itself

Abstract

purposeEndoplasmic reticulum stress (ERS) plays a crucial role in myocardial ischemia-reperfusion injury (MIRI). Cellular FLICE-inhibitory protein (cFLIP) is an essential regulator of apoptosis and plays a major role in regulating ERS. The present study aimed to investigate the effects of long isoform cFLIP (cFLIP

methodsThe cFLIP

resultscFLIP

conclusionThe expression of cFLIP

Indexed as

Myocardial Reperfusion InjuryAnimalsCASP8 and FADD-Like Apoptosis Regulating ProteinEndoplasmic Reticulum Stressp38 Mitogen-Activated Protein KinasesRatsRats, Sprague-DawleyCASP8 and FADD-Like Apoptosis Regulating Proteinp38 Mitogen-Activated Protein KinasesCellular FLICE-inhibitory ProteinEndoplasmic Reticulum StressHypoxia/reoxygenation InjuryMyocardial Ischemia-Reperfusion Injury

Identifiers

PMID34767133
OpenAlexW3213635783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.