Evidence map›Paper›PMID 34767109›Full record

ArticleClinical rheumatology2022

Computed tomography pulmonary angiography (CTPA) in Behçet's disease patients: a remarkable gender gap and time to refine the treatment strategy.

Samar Tharwat, Suzan S ElAdle, Abdel Hafeez Moshrif, Faten Ismail, Rawhya El-Shereef, Esraa A Talaat, Sara Hassanein, Yousra Hisham, Tamer A Gheita, Egyptian College of Rheumatology (ECR) Behçet’s disease study groups

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Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Samar TharwatInternal Medicine Department, Rheumatology Unit, Faculty of Medicine, Mansoura University, Mansoura, Dakahlia, Egypt.
Suzan S ElAdleRheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Abdel Hafeez MoshrifRheumatology Department, Faculty of Medicine, Al-Azhar University, Assuit, Egypt.
Faten IsmailRheumatology Department, Faculty of Medicine, Minia University, Minia, Egypt.
Rawhya El-ShereefRheumatology Department, Faculty of Medicine, Minia University, Minia, Egypt.
Esraa A TalaatRheumatology Department, Faculty of Medicine, Assuit University, Assuit, Egypt.
Sara HassaneinDiagnostic Radiology Department, Faculty of Medicine, Assiut University, Assuit, Egypt.
Yousra HishamRheumatology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Tamer A GheitaRheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt. gheitamer@hotmail.com.ORCID http://orcid.org/0000-0002-1155-9729
Egyptian College of Rheumatology (ECR) Behçet’s disease study groups
Assiut University · EGCairo University · EGMinia University · EGAl-Azhar University · EGAlexandria University · EGMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the work was to delineate the computed tomography pulmonary angiography (CTPA) findings in Behçet's disease (BD) patients with and without chest manifestations. PATIENTS AND

methodsThe study included 122 BD adults recruited from 5 Teaching University Hospitals in Egypt of those who agreed to perform a CTPA. The Arabic version of BD current activity form (BDCAF) and BD damage index (BDI) were assessed. Detailed pulmonary manifestations, examination, plain radiology chest, and CTPA findings were recorded.

resultsThe mean age of patients was 36.9 ± 11.3 years, male:female was 1.8:1, disease duration 9.6 ± 8.2 years, and age at onset 28.3 ± 8.6 years. Their mean BDCAF was 4.4 ± 2.2 and BDI 3.4 ± 1.8. There were chest manifestations in 51 (41.8%) and plain chest x-ray findings in 13 (10.7%) and CTPA findings in 31 (25.4%) in the form of pulmonary thromboembolism in 15 (12.3%), pulmonary aneurysms in 7 (5.7%), pneumonia in 5 (4.1%), interstitial lung disease in 4 (3.3%) and pleural effusion in 3 (2.5%). Patients with chest manifestations had significantly higher frequency of cardiac manifestations (15.7%) compared to those without (2.8%; p = 0.023); chest x-ray findings tended to be higher (17.6% vs 5.6%; p = 0.05) while CTPA findings were significantly detected (51% vs 7%; p < 0.0001). Higher frequency of CTPA findings were in females (p < 0.0001). Yet the rate of serious pulmonary embolisms, aneurysms, and thrombosis was exclusive in males.

conclusionMeticulous investigation of the chest manifestations is warranted in BD patients to undermine the actual magnitude of pulmonary impact. CTPA provides a realistic estimate of the extent of involvement even in asymptomatic cases. Key Points • Meticulous chest assessment is warranted in Behçet's disease patients to undermine the actual magnitude of pulmonary impact • CTPA provides a realistic estimate of the extent of involvement even in asymptomatic cases.

Indexed as

Behcet SyndromeAdultAngiographyComputed Tomography AngiographyFemaleHumansMaleMiddle AgedSex FactorsTomography, X-Ray ComputedBehçet’s diseaseComputed tomography pulmonary angiography (CTPA)Gender gapTreatment strategy

Identifiers

PMID34767109
OpenAlexW3213559037

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.