ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2022
Automated hybrid volumetric modulated arc therapy (HVMAT) for whole-breast irradiation with simultaneous integrated boost to lumpectomy area : A treatment planning study.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The use of Hybrid Techniques in Whole-Breast Radiotherapy: A Systematic Review.Technology in cancer research & treatmentPooled it
- Optimization of field setup for organs at risk sparing and beam on time in breast radiotherapy planning for a new volumetric modulated arc therapy based treatment technique.Physics and imaging in radiation oncology · 2026Article
- Optimizing Left-Sided Breast Cancer Radiotherapy: Strategy-Dependent Trade-Offs Among VMAT and Hybrid Techniques.Cancer management and research · 2026Article
- BreastWatch: A Varian Eclipse script tool for Community-Based automatic evaluation of breast treatment plans.Journal of applied clinical medical physics · 2025Article
- Automated treatment planning for whole breast irradiation with individualized tangential IMRT fields.Journal of applied clinical medical physics · 2024Article
- Review
- Ultra-Hypofractionated Whole Breast Radiotherapy with Automated Hybrid-VMAT Technique: A Pilot Study on Safety, Skin Toxicity and Aesthetic Outcomes.Breast cancer (Dove Medical Press) · 2024Article
- Reproducibility and stability of spirometer-guided deep inspiration breath-hold in left-breast treatments using an optical surface monitoring system.Journal of applied clinical medical physics · 2023Article
- Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors.Radiation oncology (London, England) · 2022Article
- Dosimetric Evaluation of Three-dimensional Conformal Radiotherapy, RapidArc, and Hybrid RapidArc Radiotherapy Techniques for Left-sided Breast Cancer.Journal of medical physicsArticle
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo develop an automated treatment planning approach for whole breast irradiation with simultaneous integrated boost using an automated hybrid VMAT class solution (HVMAT). MATERIALS AND
methodsTwenty-five consecutive patients with left breast cancer received 50 Gy (2 Gy/fraction) to the whole breast and an additional simultaneous 10 Gy (2.4 Gy/fraction) to the tumor cavity. Ipsilateral lung, heart, and contralateral breast were contoured as main organs-at-risk. HVMAT plans were inversely optimized by combining two open fields with a VMAT semi-arc beam. Open fields were setup to include the whole breast with a 2 cm flash region and to carry 80% of beams weight. HVMAT plans were compared with three tangential techniques: conventional wedged-field tangential plans (SWF), field-in-field forward planned tangential plans (FiF), and hybrid-IMRT plans (HMRT). Dosimetric differences among the plans were evaluated using Kruskal-Wallis one-way analysis of variance. Dose accuracy was validated using the PTW Octavius-4D phantom together with the 1500 2D-array.
resultsNo significant differences were found among the four techniques for both targets coverage. HVMAT plans showed consistently better PTVs dose contrast, conformity, and homogeneity (p < 0.001 for all metrics) and statistically significant reduction of high-dose breast irradiation. V55 and V60 decreased by 30.4, 26.1, and 20.8% (p < 0.05) and 12.3, 9.9, and 6.0% (p < 0.05) for SWF, FIF, and HMRT, respectively. Pretreatment dose verification reported a gamma pass-rate greater than the acceptance threshold of 95% for all HVMAT plans. In addition, HVMAT reduced the time for full planning optimization to about 20 min.
conclusionsHVMAT plans resulted in superior target dose conformity and homogeneity compared to other tangential techniques. Due to fast planning time HVMAT can be applied for all patients, minimizing the impact on human or departmental resources.
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