Evidence map›Paper›PMID 34766907›Full record

ArticleeLife2021

The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.

Astrid Kollewe, Vladimir Chubanov, Fong Tsuen Tseung, Leonor Correia, Eva Schmidt, Anna Rössig, Susanna Zierler, Alexander Haupt, Catrin Swantje Müller, Wolfgang Bildl and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Unlocking TRPM7 interactions: A database-driven quest.Computational and structural biotechnology journal · 2025
    Review
  10. Article
  11. Article
  12. Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024
    Review
  13. Review
  14. Article
  15. TRPM channels in health and disease.Nature reviews. Nephrology · 2024
    Review
  16. Dimerization of the CNNM extracellular domain.Protein science : a publication of the Protein Society · 2024
    Article
  17. Article
  18. Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Astrid Kollewe *Institute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Vladimir Chubanov *Walther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.ORCID 0000-0002-6042-4193
Fong Tsuen TseungWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Leonor CorreiaWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Eva SchmidtWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Anna RössigWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Susanna ZierlerWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Alexander HauptInstitute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0001-5647-5724
Catrin Swantje MüllerInstitute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Wolfgang BildlInstitute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Uwe SchulteInstitute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Annette NickeWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.ORCID 0000-0001-6798-505X
Bernd FaklerInstitute of Physiology II, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0001-7264-6423
Thomas GudermannWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.ORCID 0000-0002-0323-7965
Institute of Pharmacology · CZUniversity of Freiburg · DEGerman Center for Lung Research · DEJohannes Kepler University of Linz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 plays a fundamental role in the cellular uptake of divalent cations such as Zn

Indexed as

AnimalsBrainFemaleHEK293 CellsHumansMaleMiceMice, Inbred C57BLProteomicsRatsRats, WistarTRPM Cation ChannelsTrpm7 protein, mouseTrpm7 protein, ratTRPM Cation Channelsbiochemistrybrainchemical biologyhumanmouseproteomeTRPM7 complexesXenopus

Identifiers

PMID34766907
PMCPMC8616561
OpenAlexW3212374064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.