Evidence map›Paper›PMID 34766868›Full record

ArticleHuman vaccines & immunotherapeutics2022

Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile

Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira, Paulo Renato Zuquim Antas

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andreon Santos Machado da SilvaLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0001-5915-0888
Lawrence Henrique Paz AlbuquerqueLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0003-0599-5564
Carlos Germano Garrido de PonteLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0002-3952-4683
Matheus Rogério de AlmeidaLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0002-5664-3764
Sandra Elizabete Ribeiro de FariaLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0002-5254-8882
Mariana da Silva RibeiroLaboratório de Investigação Cardiovascular, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID 0000-0002-7670-2047
Evelyn Nunes Goulart da Silva PereiraLaboratório de Investigação Cardiovascular, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID 0000-0001-5511-7036
Paulo Renato Zuquim AntasLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz, Rio de Janeiro, and Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB).ORCID 0000-0002-6168-9185
Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular · BRFaculdades Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette-Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains. The early-shared strains of the BCG vaccine are stronger immunostimulators than the late-shared strains. In this study, we have employed a simple

Indexed as

Mycobacterium bovisTuberculosisBCG VaccineCytokinesDenmarkHumansRussiaBCG VaccineCytokinesCG Vaccine; strainscytokineMycobacterium bovis BCG MoreauMycobacterium bovis BCG RussiaTuberculosis

Identifiers

PMID34766868
PMCPMC8942427
OpenAlexW3212706543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.