Evidence map›Paper›PMID 34766736›Full record

ArticlePharmacology research & perspectives2021

Deprived social status is associated with decreased use of oral chemotherapy in patients with metastatic colorectal cancer: A retrospective cohort study on administrative databases in a French University Hospital.

Gwendoline Gautier, Mélodie Lucas, Thomas Vermeulin, Frederic Di Fiore, Veronique Merle

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Gwendoline GautierDepartment of Hepatogastroenterology, Rouen University Hospital, UNIROUEN, Rouen, France.
Mélodie LucasDepartment of Medical Information, Le Havre Hospital, Le Havre, France.
Thomas VermeulinDynamiques et Evènements des Soins et des Parcours Research Group, Rouen University Hospital, UNIROUEN, Rouen, France.
Frederic Di FioreDepartment of Hepatogastroenterology, Rouen University Hospital, UNIROUEN, Rouen, France.
Veronique MerleDynamiques et Evènements des Soins et des Parcours Research Group, Rouen University Hospital, UNIROUEN, Rouen, France.ORCID 0000-0002-8856-7532
UniCancer Group · FRInserm · FRUniversité de Rouen Normandie · FRUniversité Le Havre Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Factors associated with the choice of oral versus intravenous CT are not clearly established. Our purpose was to evaluate the influence of social status and home distance to hospital on the use of oral CT in patients with metastatic colorectal cancer (mCRC). This retrospective single-center study included mCRC patients between 2011 and 2017. Patient social status was assessed by European Deprivation Index (EDI) and home distance to the hospital was calculated. Univariable and multivariable logistic regression analyses were performed. One hundred and seventy-five mCRC patients were included, with 71 receiving oral CT. Most deprived patients received less oral CT (OR 0.5 [0.26, 0.96], p = .039). No association was found for road distance. Previous use of adjuvant oral CT was associated with oral CT in mCRC (OR 2.65 [1.06, 6.66], p = .038). Our results suggest that deprived social status is a factor associated with decreased use of oral CT in patients with mCRC. Clinical trial registration: no registration.

Indexed as

Social StatusAdministration, IntravenousAdministration, OralAgedAged, 80 and overAntineoplastic AgentsCohort StudiesColorectal NeoplasmsDatabases, FactualFemaleFranceHospitals, UniversityHumansMaleMiddle AgedRetrospective StudiesAntineoplastic Agentscolorectal cancerdeprivationoral chemotherapypatient care

Identifiers

PMID34766736
PMCPMC8587174
OpenAlexW3212191168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.