Evidence map›Paper›PMID 34766170›Full record

ArticleEC endocrinology and metabolic research2021

The Prevalence of Cardiovascular Disease and Other Comorbidities Among American Indian and Alaska Native Adults with Diabetes.

Joan M O'Connell, Jennifer E Rockell, Judith C Ouellet, Sherri Yoder, Kimberly E Lind, Charlton Wilson, Andrew Friedson, Spero M Manson

Open access · greenAbstract read
In one paragraph

Article in EC endocrinology and metabolic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Comorbidities among American Indian and Alaska Native People with Cancer: A Surveillance, Epidemiology, and End Results-Medicare Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Joan M O'ConnellCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Jennifer E RockellCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Judith C OuelletCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Sherri YoderRetired from the Indian Health Service, USA.
Kimberly E LindCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Charlton WilsonChief Medical Officer, Mercy Care, Phoenix, AZ, USA.
Andrew FriedsonDepartment of Economics, University of Colorado Denver, Denver, Colorado, USA.
Spero M MansonCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Colorado School of Public Health · USNative Health · USUniversity of Arizona · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Research Education CoreP30AG015292 · NIA · UNIVERSITY OF COLORADO DENVER · PI MULLER, CLEMMA JACOBSEN · 1997 to 2022
$12.3M
TRANSLATIONAL RESEARCH COREP30DK092923 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Angela Gwen Brega · 2011 to 2026
$10.2M
Dementia epidemiology, health service utilization and treatment costs among American Indian and Alaska Native EldersR01AG061189 · NIA · UNIVERSITY OF COLORADO DENVER · PI JIANG, LUOHUA, OCONNELL, JOAN M · 2019 to 2023
$2.9M
Effectiveness of advanced practice pharmacy services among American Indian and Alaska Native adults with diabetesR18DK114757 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MANSON, SPERO MARTIN, OCONNELL, JOAN M · 2017 to 2019
$681k
NIA NIH HHS P30 AG015292NIA NIH HHS R01 AG061189NIDDK NIH HHS P30 DK092923NIDDK NIH HHS R18 DK114757
6 · The paper itself

Abstract

aimsAmerican Indians and Alaska Native (AI/ANs) peoples experience significant health disparities compared to the U.S. general population. We report comorbidities among AI/ANs with diabetes to guide efforts to improve their health status.

methodsDrawing upon data for over 640,000 AI/ANs who used services funded by the Indian Health Service, we identified 43,518 adults with diabetes in fiscal year 2010. We reported the prevalence of comorbidities by age and cardiovascular disease (CVD) status. Generalized linear models were estimated to describe associations between CVD and other comorbidities.

resultsNearly 15% of AI/AN adults had diabetes. Hypertension, CVD and kidney disease were comorbid in 77.9%, 31.6%, and 13.3%, respectively. Nearly 25% exhibited a mental health disorder; 5.7%, an alcohol or drug use disorder. Among AI/ANs with diabetes absent CVD, 46.9% had 2 or more other chronic conditions; the percentage among adults with diabetes and CVD was 75.5%. Hypertension and tobacco use disorders were associated with a 71% (95% CI for prevalence ratio: 1.63 - 1.80) and 33% (1.28 - 1.37) higher prevalence of CVD, respectively, compared to adults without these conditions.

conclusionDetailed information on the morbidity burden of AI/ANs with diabetes may inform enhancements to strategies implemented to prevent and treat CVD and other comorbidities.

Indexed as

Alaska NativesAmerican IndiansCardiovascular DiseaseDiabetesKidney DiseaseMental Health Disorders

Identifiers

PMID34766170
PMCPMC8580367
OpenAlexW3128341822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.