Evidence map›Paper›PMID 34766064›Full record

ArticleJTO clinical and research reports2021

Malignant Peritoneal Mesothelioma With EWSR1-ATF1 Fusion: A Case Report.

Helen Ke, Anthony J Gill, Catriona McKenzie, James G Kench, Renee C F Chan, Nick Pavlakis, Michael Fulham, Cherry Koh, Steven Kao

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JTO clinical and research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Helen KeUniversity of Sydney, Sydney, Australia.
Anthony J GillUniversity of Sydney, Sydney, Australia.
Catriona McKenzieUniversity of Sydney, Sydney, Australia.
James G KenchUniversity of Sydney, Sydney, Australia.
Renee C F ChanElectron Microscopy Unit, Department of Anatomical Pathology, Concord Hospital, Concord, Australia.
Nick PavlakisUniversity of Sydney, Sydney, Australia.
Michael FulhamUniversity of Sydney, Sydney, Australia.
Cherry KohDepartment of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia.
Steven KaoUniversity of Sydney, Sydney, Australia.
University of Sydney · AUAsbestos Diseases Research Institute · AURoyal Prince Alfred Hospital · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant mesothelioma with EWSR1-ATF1 fusion is a rare malignancy described in young adults without asbestos exposure. To the best of our knowledge, outcomes to local and systemic therapies for this subtype of malignant mesothelioma have not been described. This case report describes the clinical course of a 19-year-old man diagnosed with malignant peritoneal mesothelioma with EWSR1-ATF1 fusion localized to the abdomen. His disease followed an aggressive course and resulted in limited survival (18 mo). There was treatment resistance to several lines of conventional local and systemic treatments for peritoneal mesothelioma and biologically targeted MET inhibition with crizotinib. More research is required in this rare subtype of peritoneal mesothelioma.

Indexed as

ATF1Case reportEWSR1Peritoneal mesothelioma

Identifiers

PMID34766064
PMCPMC8569551
OpenAlexW3207240743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.