Evidence map›Paper›PMID 34766057›Full record

ArticleSensors international2021

Silver nanoparticle based multifunctional approach for combating COVID-19.

Prince Allawadhi, Vishakha Singh, Amit Khurana, Isha Khurana, Sachin Allwadhi, Pawan Kumar, Anil Kumar Banothu, Sunitha Thalugula, Percy Jasmine Barani, Ramavath Redya Naik and 1 more

Abstract read
In one paragraph

Article in Sensors international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Potential ofBioMed research international · 2022
    Pooled it
  2. Article
  3. Biogenic silver nanoparticle as an adjuvant in an S1 subunit recombinant vaccine.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Electrochemical biosensor detection on respiratory and flaviviruses.Applied microbiology and biotechnology · 2023
    Review
  12. Article
  13. Trends in nano-platforms for the treatment of viral infectious diseases.The Korean journal of chemical engineering · 2023
    Review
  14. Review
  15. Review
  16. Review
  17. Recent developments in the use of gold and silver nanoparticles in biomedicine.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  18. Review
  19. Review
  20. Antiviral potential of nanoparticles for the treatment of Coronavirus infections.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Prince AllawadhiDepartment of Pharmacy, Vaish Institute of Pharmaceutical Education and Research (VIPER), Pandit Bhagwat Dayal Sharma University of Health Sciences (Pt. B. D. S. UHS), Rohtak - 124001, Haryana, India.
Vishakha SinghDepartment of Biotechnology, Indian Institute of Technology (IIT) Roorkee, Roorkee - 247667, Uttarakhand, India.
Amit KhuranaCentre for Biomedical Engineering (CBME), Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi - 110016, India.
Isha KhuranaDepartment of Pharmaceutical Chemistry, University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh - 160014, India.
Sachin AllwadhiDepartment of Computer Science and Engineering, University Institute of Engineering and Technology (UIET), Maharshi Dayanand University (MDU), Rohtak - 124001, Haryana, India.
Pawan KumarDepartment of Radiation Oncology, Regional Cancer Centre, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (Pt. B. D. S. PGIMS), Rohtak - 124001, Haryana, India.
Anil Kumar BanothuDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Rajendranagar, Hyderabad - 500030, PVNRTVU, Telangana, India.
Sunitha ThalugulaDepartment of Pharmacology, University College of Pharmaceutical Sciences (UCPS), Kakatiya University, Warangal - 506009, Telangana, India.
Percy Jasmine BaraniDepartment of Chemistry, Wesley Degree College for Women, Osmania University, Secunderabad - 500025, Telangana, India.
Ramavath Redya NaikZaney Pharma Innovations, Tarnaka, Hyderabad - 500007, Telangana, India.
Kala Kumar BharaniDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science (CVSc), Warangal - 506166, PVNRTVU, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a highly contagious and widespread disease that has strained the global healthcare system to the hilt. Silver nanoparticles (AgNPs) are well known for their potent antimicrobial, antiviral, immunomodulatory and biosensing properties. AgNPs have been found to be potential antiviral agent that act against many deadly viruses and is presumed to be effective against COVID-19. AgNPs can generate free radicals and reactive oxygen species (ROS) leading to apoptosis mediated cell death thereby inhibiting viral infection. The shape and size of AgNPs play an important role in its biomedical applications as alterations may result in variable biological interaction and activity. Herein, we propose that AgNPs can be utilized for effective management of the ongoing COVID-19 pandemic by highlighting the current status of AgNPs in the fight against COVID-19.

Indexed as

AntimicrobialAntiviral activityCOVID-19Cytokine stormSilver nanoparticles

Identifiers

PMID34766057
PMCPMC8169222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.