Evidence map›Paper›PMID 34765904›Full record

ArticleOTA international : the open access journal of orthopaedic trauma2021

Weight-bearing status may influence rates of radiographic healing following reamed, intramedullary fixation of diaphyseal femur fractures.

Christopher D Flanagan, Noah M Joseph, Jonathan Copp, Nicholas Romeo, Nicholas Alfonso, Adam Hirschfeld

Abstract read
In one paragraph

Article in OTA international : the open access journal of orthopaedic trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Body mass index, weight bearing, and delayed union after femoral shaft fracture nailing: a retrospective cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. A Scoring System for Predicting Nonunion After Intramedullary Nailing of Femoral Shaft Fractures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher D FlanaganDepartment of Orthopaedics, Case Western Reserve University School of Medicine.
Noah M JosephDepartment of Orthopaedics, Case Western Reserve University School of Medicine.
Jonathan CoppDepartment of Orthopaedics, Case Western Reserve University School of Medicine.
Nicholas RomeoDepartment of Orthopaedic Surgery, MetroHealth Medical Center, Cleveland, OH.
Nicholas AlfonsoDepartment of Orthopaedic Surgery, MetroHealth Medical Center, Cleveland, OH.
Adam HirschfeldDepartment of Orthopaedic Surgery, MetroHealth Medical Center, Cleveland, OH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of weight-bearing status on radiographic healing of diaphyseal femur fractures.

designRetrospective 1:1 matched cohort study.

settingSingle-level 1 trauma center.

participantsOne-hundred forty-four (N = 154) patients matched 1:1 in non-weight bearing (NWB) and weight-bearing as tolerated (WBAT) groups.

interventionNon-weight bearing following reamed, statically locked intramedullary fixation of diaphyseal femur fracture, generally due to concurrent lower extremity fracture. MAIN OUTCOME MEASUREMENT: Postoperative radiographic healing using modified Radiographic Union Scale for Tibia fractures (mRUST) scores.

resultsGroups were well matched on age, sex, race, prevalence of tobacco and alcohol use, diabetes mellitus status, Injury Severity Score, fracture pattern and shaft location, vascular injury, open fracture prevalence, and operative characteristics. Radiographic follow-up was similar between groups (231 vs 228 days,

conclusionsNon-weight bearing after intramedullary fixation of diaphyseal femur fractures delays radiographic healing, with median time to 3 cortices of bridging callous increased from 85 days in WBAT groups to 122 days in NWB groups. These results provide clinicians with an understanding of the expected postoperative course, as well as further support the need to expeditiously advance weight-bearing status.

Indexed as

femur fracturemRUSTradiographic healingweight-bearing status

Identifiers

PMID34765904
PMCPMC8575427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.