Evidence map›Paper›PMID 34765900›Full record

ArticleOTA international : the open access journal of orthopaedic trauma2021

Inpatient compliance with venous thromboembolism prophylaxis after orthopaedic trauma: results from a randomized controlled trial of aspirin versus low molecular weight heparin.

Bryce E Haac, Nathan N O'Hara, Theodore T Manson, Gerard P Slobogean, Renan C Castillo, Robert V O'Toole, Deborah M Stein

Open access · goldAbstract read
In one paragraph

Article in OTA international : the open access journal of orthopaedic trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bryce E HaacR Adams Cowley Shock Trauma Center, Department of Surgery.
Nathan N O'HaraR Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine.
Theodore T MansonR Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine.
Gerard P SlobogeanR Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine.
Renan C CastilloDepartment of Health Policy and Management, Center for Health Services and Outcomes Research and Johns Hopkins Center for Injury and Research Policy, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Robert V O'TooleR Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine.
Deborah M SteinR Adams Cowley Shock Trauma Center, Department of Surgery.
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare inpatient compliance with venous thromboembolism prophylaxis regimens.

designA secondary analysis of patients enrolled in the ADAPT (A Different Approach to Preventing Thrombosis) randomized controlled trial.

settingLevel I trauma center. PATIENTS/

participantsPatients with operative extremity or any pelvic or acetabular fracture requiring venous thromboembolism prophylaxis.

interventionWe compared patients randomized to receive either low molecular weight heparin (LMWH) 30 mg or aspirin 81 mg BID during their inpatient admission. MAIN OUTCOME MEASUREMENTS: The primary outcome measure was the number of doses missed compared with prescribed number of doses.

resultsA total of 329 patients were randomized to receive either LMWH 30 mg BID (164 patients) or aspirin 81 mg BID (165 patients). No differences observed in percentage of patients who missed a dose (aspirin: 41.2% vs LMWH: 43.3%,

conclusionsThese data should reassure clinicians that inpatient compliance is similar for low molecular weight heparin and aspirin regimens.

Indexed as

aspirinlow molecular weight heparintraumavenous thromboembolism prophylaxis

Identifiers

PMID34765900
PMCPMC8575420
OpenAlexW3199080786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.