Evidence map›Paper›PMID 34765871›Full record

ArticleJournal of emergency and critical care medicine (Hong Kong, China)2021

Predicting open wound mortality in the ICU using machine learning.

Ronald K Akiki, Rajsavi S Anand, Mimi Borrelli, Indra Neil Sarkar, Paul Y Liu, Elizabeth S Chen

Open access · diamondAbstract read
In one paragraph

Article in Journal of emergency and critical care medicine (Hong Kong, China), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ronald K AkikiAlpert Medical School, Brown University, Providence, RI, USA.ORCID 0000-0003-3459-3302
Rajsavi S AnandAlpert Medical School, Brown University, Providence, RI, USA.
Mimi BorrelliDepartment of Plastic Surgery, Rhode Island Hospital, Providence, RI, USA.
Indra Neil SarkarAlpert Medical School, Brown University, Providence, RI, USA.
Paul Y LiuDepartment of Plastic Surgery, Rhode Island Hospital, Providence, RI, USA.
Elizabeth S ChenAlpert Medical School, Brown University, Providence, RI, USA.
Brown University · USProvidence College · US

Funding

Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI ROUNDS, SHARON IRENE SMITH · 2016 to 2025
$45.0M
NIGMS NIH HHS U54 GM115677
6 · The paper itself

Abstract

backgroundOpen wounds have a significant impact on the health of patients causing pain, loss of function, and death. Labeled as a comorbid condition, open wounds represent a "silent epidemic" that affect a large portion of the US population. Due to their burden of care, open wound patients face an increased risk of ICU stay and mortality. There is a dearth of studies that investigate mortality among wound patients in the ICU. We sought to develop a model that predicts the risk of mortality among wound patients in the ICU.

methodsRandom forest and binomial logistic regression models were developed to predict the risk of mortality among open wound patients in the Medical Information Mart for Intensive Care III (MIMIC-III) database. MIMIC-III includes de-identified data for patients who stayed in critical care units of the Beth Israel Deaconess Medical Center between 2001 and 2012. Six variables were used to develop the model (wound location, gender, age, admission type, minimum platelet count and hyperphosphatemia). The Charlson Comorbidity Index (CCI) and Elixhauser Comorbidity Index were used to assess model strength.

resultsA total of 3,937 patients were included with a mean age of 76.57. Of those, 3,372 (85%) survived and 565 (15%) died during their ICU stay. The random forest model achieved an area under the curve (AUC) of 0.924. The CCI and Elixhauser models resulted in AUC of 0.528 and 0.565, respectively.

conclusionsMachine learning models may allow clinicians to provide better care and management to open wound patients in the ICU.

Indexed as

ICUMachine learningwound

Identifiers

PMID34765871
PMCPMC8579960
OpenAlexW3152678863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.