Evidence map›Paper›PMID 34765861›Full record

ArticleResearch and practice in thrombosis and haemostasis2021

Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ).

Meghan Pike, Ashley Chopek, Nancy L Young, Koyo Usuba, Mark J Belletrutti, Robyn McLaughlin, Nancy Van Eyk, Amanda Bouchard, Kristen Matteson, Victoria E Price

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  7. Article
  8. Cross-Cultural Translation of the Adolescent Menstrual Bleeding Questionnaire (AMBQ).Haemophilia : the official journal of the World Federation of Hemophilia · 2025
    Article
  9. Article
  10. Quantifying menorrhagia and overview of nonsurgical management of heavy menstrual bleeding.Hematology. American Society of Hematology. Education Program · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. New thematic calls for science atResearch and practice in thrombosis and haemostasis · 2022
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meghan PikeDivision of Pediatric Hematology-Oncology Department of Pediatrics Dalhousie University IWK Health Centre Halifax Nova Scotia Canada.ORCID https://orcid.org/0000-0002-3688-6822
Ashley ChopekCancer Care Manitoba Winnipeg Manitoba Canada.
Nancy L YoungChildren's Hospital of Eastern Ontario Research Institute Ottawa Ontario Canada.
Koyo UsubaLaurentian University Sudbury Ontario Canada.ORCID https://orcid.org/0000-0002-8850-2341
Mark J BelletruttiDepartment of Pediatrics University of Alberta Edmonton Alberta Canada.
Robyn McLaughlinDepartment of Pediatrics IWK Health Centre Halifax Nova Scotia Canada.
Nancy Van EykDepartment of Obstetrics and Gynecology IWK Health Centre Halifax Nova Scotia Canada.
Amanda BouchardDivision of Pediatric Hematology-Oncology Department of Pediatrics Dalhousie University IWK Health Centre Halifax Nova Scotia Canada.
Kristen MattesonWomen and Infants Hospital and Warren Alpert Medical School of Brown University Providence Rhode Island USA.
Victoria E PriceDivision of Pediatric Hematology-Oncology Department of Pediatrics Dalhousie University IWK Health Centre Halifax Nova Scotia Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesHeavy menstrual bleeding (HMB) affects 34% to 37% of adolescent girls. The Menstrual Bleeding Questionnaire (MBQ) is a validated measure of menstrual bleeding-specific health-related quality of life (HRQoL) for women aged ≥18 years. No similar measure existed for adolescents with HMB. PATIENTS/

methodsHMB was defined by the Pictorial Bleeding Assessment Chart (PBAC) score ≥100. In Phase 1, a focus group of adolescents with HMB adapted the MBQ, to generate the Adolescent MBQ (aMBQ). In phase 2, participants with and without HMB were recruited from clinics and self-referral. Each participant completed 3 questionnaires (aMBQ, Pediatric Quality of Life module [PedsQL]

resultsPhase 1 included five girls with a mean age of 17.1 (13-18) years. The aMBQ was adapted from the MBQ by substituting four words/phrases that altered 8 of the 20 questions and by adding 1 new question. The 21-item aMBQ has a score range of 0 to 77 (77 = worst HRQoL). Phase 2 included 52 participants: 20 with and 32 without HMB, with a mean age of 14.8 (11-17) years. The validity of the aMBQ was confirmed by a moderate correlation with PedsQL

conclusionsThe aMBQ is a valid and reliable tool to assess HRQoL in adolescents with HMB.

Indexed as

adolescentheavy menstrual bleedingmenorrhagiapatient‐reported outcome measuressurveys and questionnaires

Identifiers

PMID34765861
PMCPMC8576265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.