Evidence map›Paper›PMID 34765858›Full record

ArticleAPL bioengineering2021

Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway.

Harris B Krause, Hanna Bondarowicz, Alexis L Karls, Megan N McClean, Pamela K Kreeger

Open access · goldAbstract read
In one paragraph

Article in APL bioengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Harris B KrauseDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.ORCID https://orcid.org/0000-0003-3481-8364
Hanna BondarowiczDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Alexis L KarlsDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Training & Education to Advance Minorities in Science (TEAM-Science)R25GM083252 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2008 to 2021
$8.5M
Elucidating the network design principles of biological signal processingR35GM128873 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Megan N McClean · 2018 to 2026
$4.0M
Analysis of how quantitative cellular network variation impacts tumor progressionDP2CA195766 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KREEGER, PAMELA K · 2014 to 2014
$2.3M
NCI NIH HHS DP2 CA195766NCI NIH HHS P30 CA014520NIGMS NIH HHS R25 GM083252NIGMS NIH HHS R35 GM128873
6 · The paper itself

Abstract

Utilizing microfluidics to mimic the dynamic temporal changes of growth factor and cytokine concentrations

Identifiers

PMID34765858
PMCPMC8566012
OpenAlexW3209308179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.