Evidence map›Paper›PMID 34765744›Full record

ArticleBiochemistry and biophysics reports2021

Sexual dimorphism in inorganic mercury toxicokinetics and the attendant lipotoxic and non-lipotoxic dyslipidemia in the rat.

A D Wusu, O O Ogunrinola, O K Afolabi, E O Abam, D O Babayemi, O A Dosumu, O B Onunkwor, E A Balogun, O O Odukoya, O Ademuyiwa

Open access · goldAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

A D WusuBiochemistry Department, Lagos State University, Lagos, Nigeria.
O O OgunrinolaBiochemistry Department, Lagos State University, Lagos, Nigeria.
O K AfolabiBiochemistry Department, Ladoke Akintola University of Technology, Ogbomosho, Nigeria.
E O AbamChemical and Food Sciences Department (Biochemistry Unit), Bells University of Technology, Ota, Nigeria.
D O BabayemiBiochemistry Department, Federal University of Agriculture, Abeokuta, Nigeria.
O A DosumuBiochemistry Department, Federal University of Agriculture, Abeokuta, Nigeria.
O B OnunkworBiochemistry Department, Federal University of Agriculture, Abeokuta, Nigeria.
E A BalogunBiochemistry Department, University of Ilorin, Ilorin, Nigeria.
O O OdukoyaChemistry Department, Federal University of Agriculture, Abeokuta, Nigeria.
O AdemuyiwaBiochemistry Department, Federal University of Agriculture, Abeokuta, Nigeria.
Federal University of Agriculture · NGLagos State University · NGBells University of Technology · NGLadoke Akintola University of Technology · NGUniversity of Ilorin · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of variability in the biology of living organisms is poorly appreciated in toxicology. However, multiple lines of evidence indicate that sex-differences modulate toxicokinetics and toxicodynamics from cellular/molecular to whole animal levels resulting in different toxic responses of living organisms to xenobiotics exposure. In order to investigate the influence of sex in inorganic mercury (Hg) exposure, male and female Wistar rats were exposed to 0.5, 1.0 and 1.5 mg Hg/kg body weight orally as HgCl

Indexed as

CholesterogenesisDyslipidemiaInorganic HgPhospholipidosisSexual dimorphism

Identifiers

PMID34765744
PMCPMC8570945
OpenAlexW3158497773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.